Could a Two-Drug combo beat whipworm in kids?
NCT ID NCT07661316
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial tests whether combining two drugs—albendazole and ivermectin—works better than the standard single drug for treating whipworm infection in schoolchildren aged 6 to 15 in Honduras. Participants receive a single dose of either placebo, albendazole alone, albendazole plus ivermectin, or a fixed-dose combination tablet. The study measures cure rates and side effects, aiming to find a more effective treatment for this common intestinal worm infection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- albendazole and ivermectin
- What this could lead to
- If successful, this combination could offer a more effective, single-dose treatment for whipworm and other soil-transmitted worms, simplifying control programs in affected regions.
- What could go wrong
- This is a single trial in one region, and results may not apply elsewhere. The combination may cause more side effects than standard treatment, and cure rates may still be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ASCARIASIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Instituto de Investigaciones en Microbiología, Facultad De Ciencias, Universidad Nacional Autónoma de Honduras
Tegucigalpa, 11101, Honduras
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a livestock dewormer beat whipworm in people? a trial puts oxfendazole to the test.
- Can mapping migrant networks help end neglected tropical diseases?
- New study tracks hidden infections in migrants
- Which test best uncovers the sleeping parasite?
- Healthy volunteers swallow whipworm eggs for science
- Scientists infect volunteers with hookworms to test future vaccine