Can a livestock dewormer beat whipworm in people? a trial puts oxfendazole to the test.
NCT ID NCT04713787
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether a single dose of the experimental drug oxfendazole can cure whipworm (Trichuris trichiura) infection better than the standard treatment albendazole. About 249 adults in Peru, where whipworm is common, will receive either 400 mg or 800 mg of oxfendazole or 400 mg of albendazole. The main goal is to see which dose clears the infection, measured by the absence of worm eggs in stool samples.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- oxfendazole, an experimental anti-parasitic drug
- What this could lead to
- If oxfendazole proves more effective than albendazole, it could offer a new, single-dose cure for whipworm infections.
- What could go wrong
- This is an early phase 2 trial, so the drug may not work better than the existing treatment. Side effects and optimal dosing are still being explored.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Policlinico Asociacion Benefica Prisma
RECRUITINGSanta Clara, Maynas, Peru
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