Can mapping migrant networks help end neglected tropical diseases?
NCT ID NCT07707817
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This study tests a community-designed strategy to deliver preventive chemotherapy to mobile and migrant populations in Nigeria, who often miss treatment for neglected tropical diseases like river blindness and schistosomiasis. Researchers will work with communities to map migration patterns and set up convenient medicine distribution points. The goal is to see if this approach increases treatment coverage and brings these diseases closer to elimination.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- preventive chemotherapy medicines (ivermectin, albendazole, praziquantel) delivered through a modified mass administration strategy
- What this could lead to
- If successful, this approach could help eliminate neglected tropical diseases like river blindness and schistosomiasis in hard-to-reach communities.
- What could go wrong
- This is an implementation study, not a drug trial, so success depends on community participation and logistics. Results may not apply to other regions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 5,760 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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5 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Participants will be eligible for inclusion if they: 1. Are children aged 5-14 years or adult heads of households residing in households identified as belonging to mobile or migrant populations. 2. Reside permanently or semi-permanently within the study communities 3. Have missed one or more previous rounds of onchocerciasis and/or lymphatic filariasis MDA. 4. Are willing to provide the required biological specimens and participate in interviews, surveys, and participatory workshops or discussions as required by the study protocol. 5. Provide informed consent or assent with parental/guardian consent where applicable for minors. Exclusion Criteria: Participants will be excluded if they: 1. Are temporary visitors without meaningful residence in the study communities. 2. Do not belong to the identified mobile or migrant populations targeted by the study. 3. Are unable or unwilling to provide the required biological specimens or participate in study procedures. 4. Decline informed consent or assent, or whose parent or guardian declines consent for participation. 5. Are severely ill or have medical conditions that, in the opinion of study personnel, would make participation unsafe or inappropriate.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Recruitment is done at the Household level in selected communities
RECRUITINGOndo, Ondo, Taraba and Akwa Ibom, Nigeria
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