Filariasis
MONDO:0016075A parasitic disease caused by tissue-invasive, vector-borne nematodes which can be found anywhere in the human body and that are transmitted to humans through the bite of an infected mosquito or fly or by consumption of unsafe drinking water and which, depending on the subtype can manifest with lymphedema, dermatitis, subcutaneous edema and eye involvement. The disorder is a major public health problem in many tropical and subtropical countries. Six subtypes have been described in the literature: lymphatic filariasis, onchocerciasis, loiasis, mansonelliasis, dirofilariasis and dracunculiasis caused by Wuchereria bancrofti and filarioidea of the genus Brugia; Onchocerca volvulus; Loa loa; Mansonella; Dirofilaria; and Dracunculus medinensis, respectively. Tropical eosinophilia is considered a frequent manifestation.
15 clinical trials for this condition and its sub-types.
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Broader categories
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NIH opens study to treat parasitic infections like malaria and worms
Disease control Recruiting nowThis study at the National Institutes of Health evaluates and treats people aged 3 and older with known or suspected parasitic infections, such as malaria, intestinal worms, and others. Participants receive standard medical care, not experimental treatments. The goal is to monito…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Can mapping migrant networks help end neglected tropical diseases?
Disease control Recruiting nowThis study tests a community-designed strategy to deliver preventive chemotherapy to mobile and migrant populations in Nigeria, who often miss treatment for neglected tropical diseases like river blindness and schistosomiasis. Researchers will work with communities to map migrati…
Phase: NA • Sponsor: Uwemedimo Friday Ekpo • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Massive drug showdown: can a new pill beat river blindness for good?
Disease control Recruiting nowThis study compares two drugs, ivermectin and moxidectin, to see which works better at controlling river blindness and other common infections like intestinal worms and scabies in Angola. Over 52,000 people in 20 village groups will receive one of the drugs once a year for four y…
Phase: PHASE4 • Sponsor: Kirby Institute • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Scientists seek clues to why some get sick from parasitic worms
Knowledge-focused Recruiting nowThis study looks at how people's immune systems react to infections from parasitic worms, which can cause serious health problems like swelling, blindness, or heart disease. Researchers will evaluate and treat up to 500 participants aged 3 to 100 using standard medical tests and …
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 18, 2026 05:00 UTC
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New study tracks hidden infections in migrants
Knowledge-focused Recruiting nowThis study looks at how common certain infections are among 250 asylum seekers living in reception centers in Italy. Participants must be adults who arrived in Italy between 2 and 36 months ago. The goal is to better understand infection rates to improve health screening and care…
Phase: NA • Sponsor: IRCCS Sacro Cuore Don Calabria di Negrar • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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10,000 people tested: Cambodia's massive disease hunt begins
Knowledge-focused Recruiting nowThis study will test 10,000 people in Cambodia for 57 different infectious diseases, including dengue, flu, and malaria. Researchers want to understand how these diseases spread and who is at risk. The goal is to give local health authorities the information they need to create b…
Sponsor: Institut Pasteur du Cambodge • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC