Filariasis
MONDO:0016075A parasitic disease caused by tissue-invasive, vector-borne nematodes which can be found anywhere in the human body and that are transmitted to humans through the bite of an infected mosquito or fly or by consumption of unsafe drinking water and which, depending on the subtype can manifest with lymphedema, dermatitis, subcutaneous edema and eye involvement. The disorder is a major public health problem in many tropical and subtropical countries. Six subtypes have been described in the literature: lymphatic filariasis, onchocerciasis, loiasis, mansonelliasis, dirofilariasis and dracunculiasis caused by Wuchereria bancrofti and filarioidea of the genus Brugia; Onchocerca volvulus; Loa loa; Mansonella; Dirofilaria; and Dracunculus medinensis, respectively. Tropical eosinophilia is considered a frequent manifestation.
15 clinical trials for this condition and its sub-types.
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Broader categories
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Could a new drug combo wipe out three parasitic diseases at once?
Disease control Not yet recruitingThis large study in Fiji tests whether a new combination of drugs (moxidectin plus two others) can safely treat three common parasitic infections: lymphatic filariasis, scabies, and strongyloidiasis. About 5,100 people will receive either the new combo or the standard treatment o…
Phase: PHASE3 • Sponsor: Medicines Development for Global Health • Aim: Disease control
Last updated Jun 26, 2026 14:32 UTC
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AI app aims to help frontline workers diagnose neglected skin diseases
Diagnosis Not yet recruitingThis study tests whether a mobile app using artificial intelligence can help frontline health workers in sub-Saharan Africa better diagnose skin-related neglected tropical diseases, like leprosy and scabies. Researchers will collect images from dermatologists to train the AI, the…
Phase: NA • Sponsor: Kenya Medical Research Institute • Aim: Diagnosis
Last updated Jun 27, 2026 12:04 UTC
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New study aims to bring mental health support to people with neglected skin diseases in ghana
Knowledge-focused Not yet recruitingThis study will test a new way to care for people in Ghana who have both a neglected tropical skin disease (like leprosy or Buruli ulcer) and mental health challenges like depression or anxiety. Researchers will work with 200 affected adults and local health workers to create a G…
Phase: NA • Sponsor: Liverpool School of Tropical Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC