Multinodular goiter
MONDO:0000334Nodular goiter characterized by more than one discrete tissue mass.
Also known as: goiter, multinodular
35 clinical trials for this condition and its sub-types.
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Broader categories
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Could a tiny surgical patch preserve your voice after thyroid removal?
Symptom relief CompletedThis trial investigates whether placing a small piece of absorbable material (oxidized regenerated cellulose) over the nerves that control the voice box during total thyroidectomy can improve early voice quality. Thirty adults scheduled for thyroid surgery will be randomly assign…
Phase: NA • Sponsor: Ankara University • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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No-Drain thyroid surgery shows promise for benign nodules
Symptom relief CompletedThis study looked at whether removing benign thyroid nodules without placing a surgical drain is safe and effective. Eighty adults having thyroid surgery were randomly assigned to either the standard drain or a no-drain, sutureless technique. The goal was to see if the no-drain a…
Phase: NA • Sponsor: Minia University • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Water jet technique shields voice nerve in thyroid surgery
Symptom relief CompletedThis study tested a new method called the 'Huaxi Tunnel Technique' to protect the recurrent laryngeal nerve during thyroid surgery. The technique uses a diluted epinephrine solution injected along the nerve to create a protective tunnel, reducing the risk of injury. The trial inv…
Phase: NA • Sponsor: West China Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Tiny scope, big difference? study tests Microscope-Assisted thyroid surgery
Symptom relief CompletedThis study compared two types of thyroid surgery: one using a microscope and the standard approach. Researchers looked at blood loss, nerve damage, and low calcium levels after surgery in 74 patients with thyroid cancer or other thyroid conditions. The goal was to see if the micr…
Phase: NA • Sponsor: Shahida Islam Medical Complex • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Neck exercises after thyroid surgery show promise for faster recovery
Symptom relief CompletedThis study tested whether doing gentle neck exercises for 10 days after thyroid surgery could reduce pain and improve quality of life. 93 adults who had their thyroid removed were split into two groups: one did the exercises, the other received standard care. Researchers measured…
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Blue spray may shield nerves during thyroid surgery
Symptom relief CompletedThis study tested whether spraying a blue dye called methylene blue onto tissues during thyroid surgery helps surgeons better see and protect the nerve that controls voice and the glands that regulate calcium. 136 adults with benign thyroid nodules took part. The goal was to redu…
Phase: NA • Sponsor: Services Hospital, Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Glow-in-the-Dark dye could help surgeons avoid nerves
Knowledge-focused CompletedThis small study tested whether injecting a fluorescent dye called fluorescein sodium helps surgeons see nerves during head and neck surgery. Eight adults having open head or neck surgery received the dye through an IV. Surgeons then rated how well the glowing nerves matched stan…
Phase: PHASE2 • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Researchers measure breathing, strength, and quality of life in hospitalized endocrine patients
Knowledge-focused CompletedThis completed observational study at Uşak University examined 150 adults hospitalized in the endocrinology department. Researchers measured breathing, muscle strength, pain, fatigue, sleep quality, physical activity, balance, and nerve function. The goal was to better understand…
Sponsor: Uşak University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Blood samples aim to harmonize thyroid testing worldwide
Knowledge-focused CompletedThis completed study collected extra blood samples from 28 adults with thyroid disorders to help standardize thyroid-stimulating hormone (TSH) tests. Different labs often use different tests, making it hard to compare results. By analyzing these samples, researchers hope to make …
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC