Multinodular goiter
MONDO:0000334Nodular goiter characterized by more than one discrete tissue mass.
Also known as: goiter, multinodular
35 clinical trials for this condition and its sub-types.
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Broader categories
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New registry to see if blocking thyroid blood flow improves symptoms
Disease control ENROLLING_BY_INVITATIONThis registry study follows 100 adults who have had a procedure called thyroid embolization to treat hyperthyroidism, goiter, or thyroid nodules. The procedure uses a catheter to block blood flow to the thyroid, aiming to shrink it and reduce symptoms. Researchers will track chan…
Sponsor: Sarasota Memorial Health Care System • Aim: Disease control
Last updated Jun 26, 2026 14:53 UTC
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Urine test may spot hidden thyroid cancer, avoid unnecessary surgery
Diagnosis OngoingThis study looks at whether proteins found in urine can help doctors diagnose follicular thyroid cancer before surgery. Currently, this type of thyroid cancer can only be confirmed after removing the thyroid. Researchers will collect urine samples from 50 patients with thyroid no…
Sponsor: National Taiwan University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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Can a placental patch make neck surgery scars heal better?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether placing a placental-based allograft called Amnioeffect on the surgical wound improves scar appearance, pain, and swallowing after thyroid or parathyroid surgery. About 334 adults will be enrolled, with half receiving the graft and half getting standard ca…
Phase: NA • Sponsor: Sarasota Memorial Health Care System • Aim: Symptom relief
Last updated Jun 26, 2026 16:56 UTC
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Thyroid troubles tied to weaker muscles and more fatigue in women
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how thyroid problems impact pain, tiredness, foot shape, muscle strength, and leg function in women who have regular periods. Researchers will compare 51 women with thyroid issues to healthy women to see what differences exist. The goal is to better understand…
Sponsor: Pamukkale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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New needle method may better protect voice nerves during neck surgery
Knowledge-focused ENROLLING_BY_INVITATIONThis study compares two methods of monitoring the nerve that controls the vocal cords during thyroid and parathyroid surgery. The standard method uses a breathing tube with electrodes, while the new method uses tiny needles placed directly into the voice box cartilage. Researcher…
Phase: NA • Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Thyroid Surgery's heart impact study pulled before start
Knowledge-focused TerminatedThis study aimed to see if thyroid surgery changes the thickness of the carotid artery, which is a sign of heart disease risk. It planned to measure artery thickness before and after surgery in adults with various thyroid conditions. However, the study was withdrawn before enroll…
Sponsor: Istituto Auxologico Italiano • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Brain scans reveal hidden links between body diseases and metabolism
Knowledge-focused OngoingThis study watches 200 people with lung, gut, or hormone diseases over time using special brain scans (PET). It aims to see how these diseases change brain activity and whether those changes can predict tumor return, spread, or survival. No new treatment is tested—just observatio…
Sponsor: The First Affiliated Hospital of Zhengzhou University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC