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Tiny scope, big difference? study tests Microscope-Assisted thyroid surgery

NCT ID NCT07488858

Symptom relief Sponsor: Shahida Islam Medical Complex Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two types of thyroid surgery: one using a microscope and the standard approach. Researchers looked at blood loss, nerve damage, and low calcium levels after surgery in 74 patients with thyroid cancer or other thyroid conditions. The goal was to see if the microscope technique leads to fewer complications and better recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

74 people

The number who actually took part.

Started

Dec 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both Male or female patients. * Patients aged 18 to 65 years undergoing thyroidectomy for benign or malignant thyroid disease. * Patients with multinodular goiter, Grave's disease, thyroid carcinoma indicated for surgery based on their workup. * Candidates scheduled for unilateral lobectomy, subtotal thyroidectomy, or total thyroidectomy. * Patients with preoperative normal vocal cord mobility confirmed by laryngoscopy. Hemodynamically stable patients without significant comorbidities affecting surgery or anesthesia based on ASA classification (Class I-III). • Patients who provide informed consent to participate in the study. Exclusion Criteria: • Prior history of prior thyroid surgery. * Patients with evidence of lateral lymph node metastasis or local invasion on preoperative imaging (ultrasonography or computed tomography). * Patients with pre-existing hypocalcemia or parathyroid disorders. * Patients with severe medical comorbidities, including uncontrolled diabetes (HbA1c \> 8%), chronic kidney disease (eGFR \< 30 mL/min/1.73m²), liver cirrhosis (Child-Pugh class B or C), or coagulopathy (INR \> 1.5 or platelet count \< 50,000/μL), will be excluded from the study. * Pregnant or lactating women. * Patients with invasive thyroid carcinoma, anaplastic thyroid carcinoma, or thyroid lymphoma requiring extensive radical surgery.

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Conditions

The condition(s) this trial relates to.

Graves disease multinodular goiter thyroid cancer thyroid gland carcinoma Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Thyroid cancer Thyroid surgeries

Contacts and locations

Locations

  • Shaikh Zayed Hospital, Lahore

    Lahore, Punjab Province, 60000, Pakistan

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