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Simple blood test during thyroid surgery may predict dangerous calcium drop

NCT ID NCT07701824

Completed Knowledge-focused Sponsor: Emrecan Deniz Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study investigates whether measuring ionized calcium levels before, during, and after total thyroidectomy can predict which patients will develop low calcium levels (hypocalcemia) after surgery. Researchers will track calcium and parathyroid hormone levels in 327 adults undergoing thyroid removal for conditions like goiter or thyroid cancer. The goal is to identify early warning signs that could help doctors prevent complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test that helps doctors predict and prevent dangerously low calcium levels after thyroid surgery.
What could go wrong
This is an observational study, not a treatment trial, so it cannot prove that using these measurements improves patient outcomes. Results may not apply to all hospitals or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypoparathyroidism multinodular goiter papillary carcinoma toxic multinodular goitre

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE HYPOCALCEMIA POSTOPERATIVE HYPOPARATHYROIDISM TOTAL THYROIDECTOMY

Contacts and locations

Locations

  • Basaksehir Cam and Sakura City Hospital

    Başakşehir, Turkey (Türkiye)

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