Cure My Disease

Don't miss your cure!

 Log in / Sign up

Simple blood test during thyroid surgery may predict dangerous calcium drop

NCT ID NCT07701824

Knowledge-focused Sponsor: Emrecan Deniz Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study investigates whether measuring ionized calcium levels before, during, and after total thyroidectomy can predict which patients will develop low calcium levels (hypocalcemia) after surgery. Researchers will track calcium and parathyroid hormone levels in 327 adults undergoing thyroid removal for conditions like goiter or thyroid cancer. The goal is to identify early warning signs that could help doctors prevent complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test that helps doctors predict and prevent dangerously low calcium levels after thyroid surgery.
What could go wrong
This is an observational study, not a treatment trial, so it cannot prove that using these measurements improves patient outcomes. Results may not apply to all hospitals or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

327 people

The number who actually took part.

Started

Jun 2025

Finished

Jul 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients admitted to Başakşehir Çam and Sakura City Hospital who are scheduled to undergo total thyroidectomy.

Ages

18 to 75 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 to 75 years * Present to the General Surgery Clinic of Başakşehir Çam and Sakura City Hospital * Diagnosis of thyroid disorders according to ICD code E07 * Scheduled to undergo total thyroidectomy due to toxic multinodular goiter, multinodular goiter, or papillary carcinoma * Provide informed consent to participate in the study. Exclusion Criteria: * Patients with preoperative parathyroid disorders associated hypocalcemia or hypercalcemia. * Patients with a history of previous thyroidectomy * Patients with a history of previous parathyroidectomy * Patients with a history of previous neck surgery. * Patients with chronic kidney disease. * Patients with a history of non-thyroid malignancy.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Multinodular goiter are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hypoparathyroidism multinodular goiter papillary carcinoma toxic multinodular goitre

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative hypocalcemia Postoperative hypoparathyroidism Total thyroidectomy

Contacts and locations

Locations

  • Basaksehir Cam and Sakura City Hospital

    Başakşehir, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.