Neck nerve block may dampen surgery stress — trial puts it to the test

NCT ID NCT07721818

Not yet recruiting Symptom relief Sponsor: University Hospital Dubrava Source: ClinicalTrials.gov ↗

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This trial tests whether a targeted nerve block in the neck can lower the body's stress response during total thyroidectomy. Researchers will measure stress and inflammation markers in the saliva of 48 patients, half of whom receive the block plus standard anesthesia, while the other half receive anesthesia alone. The goal is to see if the block leads to a calmer surgical experience and faster recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ultrasound-guided bilateral intermediate cervical plexus block
What this could lead to: If it works, this could lead to a routine nerve block that reduces stress and speeds recovery after thyroid surgery.
What could go wrong: This is a small, early-phase trial with only 48 participants, so results may not apply broadly. The block carries rare risks like infection or nerve injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL PLEXUS BLOCK SALIVA COLLECTION SURGICAL STRESS RESPONSE TOTAL THYROIDECTOMY

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