Movement disorder
MONDO:0005395Neurological conditions resulting in abnormal voluntary or involuntary movement, which may impact the speed, fluency, quality and ease of movement.
Also known as: movement disease, movement disorder, movement disorders
805 clinical trials for this condition and its sub-types, 108 tagged with Movement disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Movement disorder
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Extrapyramidal and movement disease 0 trials · 149 incl. sub-types
1 sub-type
- Dystonic disorder 65 trials · 149 incl. sub-types Sub-types →
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Cerebellar ataxia 40 trials · 144 incl. sub-types
1 sub-type
- Hereditary cerebellar ataxia 0 trials · 116 incl. sub-types Sub-types →
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Multiple system atrophy 110 trials · 119 incl. sub-types
4 sub-types
- Pure autonomic failure 18 trials
- Multiple system atrophy, parkinsonian type 12 trials
- Multiple system atrophy, cerebellar type 3 trials
- Striatonigral degeneration 0 trials Sub-types →
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Essential tremor 102 trials · 104 incl. sub-types
6 sub-types
- Tremor, hereditary essential, 1 2 trials
- Tremor, hereditary essential, 2 0 trials
- Tremor, hereditary essential, 3 0 trials
- Tremor, hereditary essential, 4 0 trials
- Tremor, hereditary essential, 5 0 trials
- Tremor, hereditary essential, 6 0 trials
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Progressive supranuclear palsy 73 trials · 77 incl. sub-types
4 sub-types
- Supranuclear palsy, progressive, 1 5 trials
- Atypical progressive supranuclear palsy syndrome 1 trial · 4 incl. sub-types Sub-types →
- Supranuclear palsy, progressive, 2 0 trials
- Supranuclear palsy, progressive, 3 0 trials
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Huntington disease 76 trials
2 sub-types
- Juvenile Huntington disease 1 trial
- Westphal disease 0 trials
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Progressive non-fluent aphasia 23 trials · 44 incl. sub-types
1 sub-type
- Semantic dementia 32 trials Sub-types →
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Behavioral variant of frontotemporal dementia 21 trials · 42 incl. sub-types
3 sub-types
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Tourette syndrome 41 trials
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Corticobasal syndrome 19 trials
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Frontotemporal dementia with motor neuron disease 13 trials · 19 incl. sub-types
7 sub-types
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 1 5 trials
- Amyotrophic lateral sclerosis type 10 3 trials
- Amyotrophic lateral sclerosis type 6 1 trial
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 2 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 3 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 4 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 6 0 trials
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Chronic tic disorder 15 trials
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Choreatic disease 11 trials
5 sub-types
- Chorea gravidarum 0 trials
- Chorea, benign familial 0 trials
- Chorea, remitting, with nystagmus and cataract 0 trials
- Choreoathetosis, familial inverted 0 trials
- Hereditary progressive chorea without dementia 0 trials
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Neurodegeneration with brain iron accumulation 1 trial · 8 incl. sub-types
14 sub-types
- Neurodegeneration with brain iron accumulation 5 4 trials
- Pantothenate kinase-associated neurodegeneration 4 trials Sub-types →
- PLA2G6-associated neurodegeneration 1 trial Sub-types →
- Kufor-Rakeb syndrome 0 trials Sub-types →
- Woodhouse-Sakati syndrome 0 trials
- Aceruloplasminemia 0 trials
- Early-onset progressive encephalopathy-spastic ataxia-distal spinal muscular atrophy syndrome 0 trials
- Fatty acid hydroxylase-associated neurodegeneration 0 trials
- Neurodegeneration with brain iron accumulation 4 0 trials
- Neurodegeneration with brain iron accumulation 6 0 trials
- Neurodegeneration with brain iron accumulation 7 0 trials
- Neurodegeneration with brain iron accumulation 8 0 trials
- Neurodegeneration with brain iron accumulation 9 0 trials
- Neuroferritinopathy 0 trials
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Arthrogryposis 4 trials · 6 incl. sub-types
5 sub-types
- Freeman-Sheldon syndrome 1 trial Sub-types →
- Congenital contractural arachnodactyly 1 trial
- Boylan dew greco syndrome 0 trials
- Distal arthrogryposis Moore weaver type 0 trials
- Massa casaer ceulemans syndrome 0 trials
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Inherited Creutzfeldt-Jakob disease 5 trials
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Primary orthostatic tremor 5 trials
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Clonic hemifacial spasm 4 trials
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Familial congenital mirror movements 3 trials
4 sub-types
- Mirror movements 1 and/or agenesis of the corpus callosum 0 trials Sub-types →
- Mirror movements 2 0 trials
- Mirror movements 3 0 trials
- Mirror movements 4 0 trials
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Transient tic disorder 3 trials
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Opsoclonus-myoclonus syndrome 2 trials
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Lafora disease 1 trial
2 sub-types
- Myoclonic epilepsy of Lafora 1 0 trials
- Myoclonic epilepsy of Lafora 2 0 trials
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Unverricht-Lundborg syndrome 1 trial
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Benign shuddering attacks 1 trial
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Myoclonus, familial 1 trial
2 sub-types
- Myoclonus, familial, 1 0 trials
- Myoclonus, familial, 2 0 trials
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Psychogenic movement disorders 1 trial
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PRRT2-associated paroxysmal movement disorder 0 trials · 1 incl. sub-types
3 sub-types
- Episodic kinesigenic dyskinesia 1 1 trial
- Infantile convulsions and choreoathetosis 0 trials
- Seizures, benign familial infantile, 2 0 trials
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Intellectual disability-hyperkinetic movement-truncal ataxia syndrome 0 trials · 1 incl. sub-types
1 sub-type
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Huntington disease-like 3 0 trials
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2 sub-types
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Sandifer syndrome 0 trials
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Brain-lung-thyroid syndrome 0 trials
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1 sub-type
- Torsion dystonia 2 0 trials
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Epilepsy with myoclonic absences 0 trials
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Hereditary geniospasm 0 trials
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Hyperekplexia 0 trials
2 sub-types
- Hereditary hyperekplexia 0 trials Sub-types →
- Sporadic hyperekplexia 0 trials
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Isolated facial myokymia 0 trials
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Kuru 0 trials
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Lingual-facial-buccal dyskinesia 0 trials
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Neuroacanthocytosis 0 trials
2 sub-types
- VPS13A-related neurodegenerative disease 0 trials
- XK-related neurodegenerative disease 0 trials
Most studied deeper sub-types
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Daily pill takes aim at a rare brain disease that mimics Parkinson's
Disease control Not yet recruitingResearchers are testing an experimental oral drug called ONO-2808 in adults with the Parkinsonian subtype of multiple system atrophy (MSA-P), a rare and progressive brain disorder. The phase 3 trial enrolls about 486 people in the early stages of the disease, within five years of…
Phase 3 • Sponsor: Ono Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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Can a gene therapy rewire brain cells to ease Parkinson's?
Disease control Not yet recruitingThis early trial tests a gene therapy called ZR001 in people with moderately advanced Parkinson's disease. ZR001 is injected into a brain region involved in movement, and a very low dose of an existing drug is then used to activate the therapy. The goal is to see if this approach…
Phase 1 • Sponsor: Qianfoshan Hospital • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Stem cells take on Parkinson's: first safety trial begins
Disease control Not yet recruitingThis early-stage study tests whether stem cells from umbilical cords are safe for people with Parkinson's disease. About 20 adults will receive either the cells or a placebo, and researchers will monitor side effects and any changes in movement. The goal is to see if this approac…
Phase 1 • Sponsor: Liaoning Medical Diagnosis and Treatment Technology Research and Development Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Can acupuncture and magnetic pulses restore arm function after a stroke?
Disease control Not yet recruitingThis study tests whether adding scalp acupuncture to repetitive transcranial magnetic stimulation (rTMS) improves arm movement in stroke survivors. Researchers will compare two groups: one getting rTMS plus standard rehab, and another getting rTMS plus scalp acupuncture and stand…
Sponsor: Debiao Kong • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Could a sleep aid also ease Parkinson's movement problems?
Symptom relief Not yet recruitingThis study tests whether the sleep medication lemborexant can improve both sleep and motor symptoms in people with Parkinson's disease. Forty-four participants will take either lemborexant or a placebo nightly for 28 days. Researchers will measure changes in sleep quality and mov…
Phase 4 • Sponsor: YangPan • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Zapping the brain to steady Parkinson's tremors and steps
Symptom relief Not yet recruitingThis study tests whether a non-invasive brain stimulation technique called temporal interference stimulation can improve tremor and walking difficulties in people with Parkinson's disease. Fifty participants will be randomly assigned to receive either real or sham stimulation dai…
Sponsor: YangPan • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Can a home workout boost brain and body in Parkinson's?
Symptom relief Not yet recruitingThis study tests a 16-week home-based exercise program for people with Parkinson's disease. Fifty participants will either do aerobic and resistance training or just stretching. The goal is to see if the program increases daily physical activity, improves thinking, and enhances q…
Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Sound waves aimed at brain may quiet shaky hands
Symptom relief Not yet recruitingThis study tests whether a precise beam of ultrasound directed at a small part of the brain (the dentate nucleus) can reduce tremor. First, 30 healthy volunteers will have their hand tremor measured during ultrasound to find the best settings. Then, 30 people with essential tremo…
Sponsor: KU Leuven • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC