Microcephaly
MONDO:0001149A congenital or acquired developmental disorder in which the circumference of the head is smaller than normal for the person's age and sex.
Also known as: microcephalus, microcephaly, microcephaly (disease), microencephaly
12 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Gene therapy aims to halt rare childhood paralysis disorder
Disease control Recruiting nowThis trial tests a single injection of MELPIDA, a gene therapy that delivers a working copy of the AP4M1 gene directly into the spinal fluid of children with SPG50. SPG50 is a rare genetic condition that causes muscle stiffness, intellectual disability, and developmental delays. …
Phase: PHASE1, PHASE2 • Sponsor: Elpida Therapeutics SPC • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Can intensive Play-Based therapy help kids with brain injuries move better?
Disease control Recruiting nowThis study looks at how well a special intensive therapy called ACQUIRE Therapy works for children with motor problems caused by conditions like cerebral palsy, autism, or brain injury. The therapy involves many hours of play-based exercises each day, often with a cast or splint …
Sponsor: Virginia Polytechnic Institute and State University • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Breathing device may shield heart during breast cancer radiation
Symptom relief Recruiting nowThis study tests whether using a CPAP breathing mask during radiation therapy for early-stage breast cancer can lower radiation doses to the heart and lungs. About 53 women with left-sided breast cancer will receive radiation with CPAP support. The goal is to reduce long-term hea…
Phase: PHASE2, PHASE3 • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Can a simple mouthpiece outperform CPAP for brain fog in sleep apnea?
Symptom relief Recruiting nowThis study tests whether a dental mouthpiece (MAD) works as well as a CPAP machine to improve thinking and memory in people with sleep apnea who also have mild memory problems. About 260 adults aged 45 and older will be randomly assigned to use either device for one year. Researc…
Phase: NA • Sponsor: National University Hospital, Singapore • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Could a sleep apnea machine fix a tricky blood pressure problem?
Symptom relief Recruiting nowThis study looks at whether using a CPAP machine at night can lower dangerously high blood pressure that happens when people with autonomic failure lie down. About 12 participants will use CPAP or a placebo pill/patch. The main goal is to see if CPAP reduces blood pressure while …
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Scientists launch study to unravel rare MEHMO syndrome
Knowledge-focused Recruiting nowThis observational study follows 150 people with MEHMO syndrome or related conditions to better understand how the disease progresses. Researchers will collect medical history, imaging, and lab samples to find biological markers that could help monitor the disease. No treatment i…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Sleep apnea study aims to track 1,000 patients for better care
Knowledge-focused Recruiting nowThis study will follow 1,000 adults in Spain who are suspected of having obstructive sleep apnea (OSA) and daytime sleepiness. Participants will undergo standard sleep tests, blood pressure monitoring, and fill out questionnaires about their quality of life and sleepiness. Resear…
Sponsor: Hospital San Pedro de Logroño • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New registry aims to unlock secrets of rare dwarfism disorders
Knowledge-focused Recruiting nowThis study creates a registry to collect health information from 200 people with rare forms of primordial dwarfism, such as MOPDII and Meier-Gorlin syndrome. Researchers hope to learn how these conditions change over a person's lifetime and improve future care. Participants provi…
Sponsor: Nemours Children's Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC