Could a sleep apnea machine fix a tricky blood pressure problem?

NCT ID NCT03312556

Recruiting now Symptom relief Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether using a CPAP machine at night can lower dangerously high blood pressure that happens when people with autonomic failure lie down. About 12 participants will use CPAP or a placebo pill/patch. The main goal is to see if CPAP reduces blood pressure while lying flat.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: continuous positive airway pressure (CPAP) device
What this could lead to: If it works, CPAP could offer a simple, non-drug way to manage supine hypertension in people with autonomic failure.
What could go wrong: This is a very small early study (12 people) testing a short-term effect. It may not work for everyone, and CPAP can be uncomfortable to use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder microcephaly 6, primary, autosomal recessive multiple system atrophy pure autonomic failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTONOMIC FAILURE SUPINE HYPERTENSION

Contacts and locations

Locations

Autonomic Dysfunction Center/ Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States

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