Could a sleep apnea machine fix a tricky blood pressure problem?

NCT ID NCT03312556

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether using a CPAP machine at night can lower dangerously high blood pressure that happens when people with autonomic failure lie down. About 12 participants will use CPAP or a placebo pill/patch. The main goal is to see if CPAP reduces blood pressure while lying flat.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

continuous positive airway pressure (CPAP) device

What this could lead to

If it works, CPAP could offer a simple, non-drug way to manage supine hypertension in people with autonomic failure.

What could go wrong

This is a very small early study (12 people) testing a short-term effect. It may not work for everyone, and CPAP can be uncomfortable to use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder microcephaly 6, primary, autosomal recessive multiple system atrophy pure autonomic failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Autonomic Dysfunction Center/ Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact