Can a simple mouthpiece outperform CPAP for brain fog in sleep apnea?
NCT ID NCT06983769
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a dental mouthpiece (MAD) works as well as a CPAP machine to improve thinking and memory in people with sleep apnea who also have mild memory problems. About 260 adults aged 45 and older will be randomly assigned to use either device for one year. Researchers will track changes in cognitive tests, blood pressure, and brain scans to see which treatment helps more.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National University Hospital
RECRUITINGKent Ridge, Please Select, 267383, Singapore
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