Lumbar disk herniation, susceptibility to

This study compares two types of implants used in spinal fusion surgery: 3D-printed cages and titanium-coated cages. The goal is to see which leads to better bone fusion and less disability for patients with herniated discs or degenerative spine disease. About 78 adults undergoin…

This early-stage trial tests whether injecting stem cells from donated umbilical cords into the spine can help repair degenerated discs in people with lower back and leg pain. Twenty patients who have not improved with other treatments will receive the injection right after a min…

This study tests a new gel, MegaShield-SP, to see if it prevents scar tissue after spine surgery better than an existing gel. About 80 adults aged 20-70 with a herniated disc or spinal stenosis will receive one of the two gels during surgery. Researchers will measure scar formati…

This study tests a new artificial disc implant (PerQdisc) placed during surgery for a herniated disc. The goal is to see if it is safe and helps reduce back and leg pain. About 50 adults with a single herniated disc in the lower back will take part. The implant is meant to replac…

This study looks at whether showering once or twice with a special antiseptic soap before lumbar disc herniation surgery reduces the risk of surgical site infections. 86 participants will be randomly assigned to shower either the night before surgery or both the night before and …

This study tests whether a specific ultrasound-guided nerve block can reduce pain after elective lower back surgery better than the usual method of injecting pain medicine into the wound. Adults aged 18-65 undergoing surgery for conditions like a herniated disc or spinal stenosis…

This study tests whether a targeted nerve block (retrolaminar block) provides better pain relief after lumbar discectomy than the standard method of injecting pain medicine into the surgical wound. 130 adults having elective single-level herniated disc surgery will be randomly as…

This study looks at two different ways to manage pain after lower back surgery without relying on drugs. About 267 adults will be randomly assigned to either standard care or an enriched pain management plan. The goal is to see which approach better reduces pain and helps people …

This study looks at two ways to numb people for lower back surgery: general anesthesia (being fully asleep) plus a nerve block, or spinal anesthesia (numbing only the lower body) plus a nerve block. The goal is to see which approach helps patients recover better and feel less pai…

This study compares two common procedures for chronic back pain caused by a slipped disc or narrowed spine: a steroid injection and a nerve-targeting radiofrequency treatment. Researchers will track pain levels in 200 adults right after the procedure and three weeks later. The go…

This study looks at whether 8 weeks of Pilates exercises can help middle-aged women (45-60 years old) with long-term lower back pain from a herniated disc. Researchers will measure balance, ankle strength, and body awareness in 30 women. Half will do Pilates, and the other half w…

This study looks at whether a specific nerve block (called an erector spinae plane block) can improve pain control after surgery for a slipped disc in the lower back. Researchers will track pain scores, opioid use, how soon patients can walk, and how long they stay in the hospita…

This study tests whether adding virtual reality (VR) to standard physical therapy helps people recover better after lumbar disc surgery. About 46 adults who had surgery on their lower back will either get standard therapy or standard therapy plus a 20-minute VR session. Researche…

This study is developing and testing a mobile app that guides people with lumbar disc herniation through fascia exercises. Participants will be taught exercises by a physiotherapist and then use either the app, a home brochure, or standard lumbar stabilization exercises. The goal…

This study compares two types of nerve blocks—quadratus lumborum block and retrolaminar block—for pain after lumbar disc surgery. About 84 adults having elective back surgery will receive one of the two blocks before surgery. Researchers will measure pain scores, opioid use, and …

This study aimed to see if a rapid whole genome sequencing test on amniotic fluid could give faster genetic diagnoses for fetuses with suspected genetic diseases. Researchers planned to compare results from amniotic fluid and blood samples from up to 90 families. However, the stu…