Lipoid nephrosis
MONDO:0006835A glomerular disorder characterized by the electron microscopic finding of loss of podocyte foot processes. Light microscopic examination does not show glomerular changes. Patients present with proteinuria and nephrotic syndrome.
Also known as: lipoid nephrosis, minimal change disease, minimal change glomerulonephritis, minimal change nephropathy, nil disease, MCNS, idiopathic minimal change nephrotic syndrome, minimal change glomerulopathy
33 clinical trials for this condition and its sub-types.
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Can a single Immune-Targeting drug quiet an autoimmune kidney disease?
Disease control OngoingThis trial tests whether rituximab, an infusion drug that calms certain immune cells, can help people with idiopathic membranous nephropathy and nephrotic syndrome. Participants receive either rituximab or a placebo, and the study tracks how many achieve a significant reduction i…
Phase: PHASE3 • Sponsor: Shoichi Maruyama MD PhD • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Could less steroid be just as good for kids with kidney disease?
Disease control OngoingThis study tests whether a lower dose of the steroid prednisone can treat relapses of nephrotic syndrome in children as effectively as the standard dose. Fifty children aged 1 to 18 with active relapses will be randomly assigned to either the reduced-dose or standard-dose regimen…
Phase: PHASE3 • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Scientists hunt for genes behind kidney disease
Knowledge-focused OngoingThis study aims to find the genetic causes of kidney diseases like FSGS and nephrotic syndrome. Researchers will collect saliva and urine samples from up to 2,050 participants, including patients and their family members, as well as healthy volunteers. The goal is to understand w…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC