Lipoid nephrosis
MONDO:0006835A glomerular disorder characterized by the electron microscopic finding of loss of podocyte foot processes. Light microscopic examination does not show glomerular changes. Patients present with proteinuria and nephrotic syndrome.
Also known as: lipoid nephrosis, minimal change disease, minimal change glomerulonephritis, minimal change nephropathy, nil disease, MCNS, idiopathic minimal change nephrotic syndrome, minimal change glomerulopathy
33 clinical trials for this condition and its sub-types.
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Cheaper plasma treatment may rival albumin for kidney swelling in kids
Disease control Not yet recruitingThis study compares two treatments—albumin and fresh frozen plasma—for children with idiopathic nephrotic syndrome who have fluid buildup that doesn't respond to standard diuretics. The goal is to see which approach resolves swelling faster and more safely. Fifty-six children age…
Phase: NA • Sponsor: Qamar Shafiq • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Promising antibody therapy may help kidney patients stay Relapse-Free longer
Disease control Not yet recruitingThis study tests a drug called obinutuzumab in 10 adults with a kidney condition called nephrotic syndrome that keeps coming back despite standard treatments. The goal is to see if a single course can keep patients relapse-free for at least 12 months by deeply depleting certain i…
Phase: PHASE2 • Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Disease control
Last updated Jun 27, 2026 08:14 UTC
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Could a 12-week steroid course be enough for kidney disease?
Disease control Not yet recruitingThis study compares a 12-week steroid course to the standard 24-week course for adults with steroid-sensitive nephrotic syndrome, a kidney condition that causes protein leakage and swelling. Researchers want to see if the shorter treatment can keep the disease from coming back ju…
Phase: PHASE4 • Sponsor: First Affiliated Hospital of Wenzhou Medical University • Aim: Disease control
Last updated Jun 26, 2026 12:59 UTC
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A simple blood test may reveal kidney damage in lupus — no biopsy needed?
Diagnosis Not yet recruitingThis study asks whether levels of uromodulin, a protein in the blood, can indicate the severity of kidney damage in people with lupus nephritis. Researchers will compare uromodulin levels with kidney biopsy results from 90 participants, including those with different classes of l…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Aug 15, 2026 00:00 UTC