Cheaper plasma treatment may rival albumin for kidney swelling in kids
NCT ID NCT07685093
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study compares two treatments—albumin and fresh frozen plasma—for children with idiopathic nephrotic syndrome who have fluid buildup that doesn't respond to standard diuretics. The goal is to see which approach resolves swelling faster and more safely. Fifty-six children aged 2 to 12 will receive one of the two treatments alongside a diuretic, and researchers will track how quickly edema improves, hospital stay length, and any complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Human albumin 20% and fresh frozen plasma
- What this could lead to
- If one treatment works better, it could offer a safer or cheaper way to reduce swelling in children with nephrotic syndrome.
- What could go wrong
- This is a small, early-stage study with only 56 children, so results may not apply broadly. Both treatments carry risks like infection or allergic reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 56 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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2 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children diagnosed with an idiopathic nephrotic syndrome and diuretic resistant as per the definition • Children of either gender. • Children of 2-12 years of age Exclusion Criteria: * • Patients with secondary nephrotic syndrome/heart failure/hepatic dysfunction/severe renal impairment • Children with severe sepsis/hemodynamically unstable. • Children who had recent exchange transfusion • Parents refused to follow up
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.