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Lichen sclerosus et atrophicus

MONDO:0007899

A chronic inflammatory process affecting the skin. It is characterized by the presence of white, indurated plaques, epidermal atrophy, and fibrosis of the upper dermis. It usually appears in the vulva and penis.

Also known as: lichen sclerosus et atrophicus, LSA, lichen SCLEROSUS ET ATROPHICUS, lichen sclerosis, lichen sclerosis et atrophicus, lichen sclerosus

19 clinical trials for this condition and its sub-types.

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Sub-types

Vulvar lichen sclerosus (14)

Broader categories

Disease (680) Inflammatory disease (332) Hereditary disease (176) Skin disorder (132) Dermatitis (62) Human disease (14) Hereditary skin disorder (6) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by developmental or physiological process (0)
Trials to join now! 9 Not yet recruiting 4 Not yet finished but already full! 1 Completed 5
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  • Can a JAK-Inhibitor cream recolor white patches caused by cancer treatment?

    Disease control Ongoing

    This study tests whether a topical cream containing ruxolitinib can safely restore skin color in people who develop white patches (vitiligo-like depigmentation) as a side effect of cancer immunotherapy. The cream is applied twice daily for 52 weeks. Researchers will measure how m…

    Phase: PHASE2 • Sponsor: University of Zurich • Aim: Disease control

    Last updated Jul 26, 2026 00:00 UTC

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