Lichen sclerosus et atrophicus
MONDO:0007899A chronic inflammatory process affecting the skin. It is characterized by the presence of white, indurated plaques, epidermal atrophy, and fibrosis of the upper dermis. It usually appears in the vulva and penis.
Also known as: lichen sclerosus et atrophicus, LSA, lichen SCLEROSUS ET ATROPHICUS, lichen sclerosis, lichen sclerosis et atrophicus, lichen sclerosus
34 clinical trials for this condition and its sub-types.
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Broader categories
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New study tests PRP against standard creams for chronic vulvar condition
Disease control Not yet recruitingThis study compares three treatments for vulvar lichen sclerosus, a chronic skin condition causing itching and pain. 45 women aged 30-80 will receive either a steroid cream, an immune-modulating cream, or platelet-rich plasma (PRP) injections. The goal is to see which approach be…
Phase: NA • Sponsor: Milosz Pietrus • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Can a daily drink ease vaginal dryness in lichen sclerosus?
Symptom relief Not yet recruitingThis study tests whether an oral collagen supplement (Collagendep) can reduce vulvar dryness in 40 women with genital lichen sclerosus who are also receiving fat grafting. Participants take the supplement daily for 4 months. The main goal is to see if dryness improves, with secon…
Phase: NA • Sponsor: San Gallicano Dermatological Institute IRCCS • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Hormone combo may offer new hope for vulvodynia sufferers
Symptom relief Not yet recruitingThis study tests whether a cream containing both testosterone and estrogen works better than estrogen alone to reduce pain during sex for women with vulvodynia. About 44 adult women with moderate to severe pain will use one of the two creams daily. The goal is to find a more effe…
Phase: PHASE2, PHASE3 • Sponsor: TriHealth Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Skin deep: european study probes the hidden emotional toll of skin diseases
Knowledge-focused Not yet recruitingThis study looks at how people with skin conditions (like eczema, psoriasis, or skin cancer) manage stress, feel lonely, and bounce back from challenges. Researchers will compare 375 adults with and without skin disease across 15 European countries using questionnaires. The goal …
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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30,000 blood samples could revolutionize rapid disease testing
Knowledge-focused Not yet recruitingThis study will collect blood samples from 30,000 adults in the UK with various health conditions, including blood clots, infections, heart disease, diabetes, and more. The samples will be used to develop and fine-tune new diagnostic tests for the cobas® lumira device, which allo…
Sponsor: LumiraDx UK Limited • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC