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Lepromatous leprosy

MONDO:0005127

A chronic communicable infection which is a principal or polar form of leprosy. This disorder is caused by mycobacterium leprae and produces diffuse granulomatous skin lesions in the form of nodules, macules, or papules. The peripheral nerves are involved symmetrically and neural sequelae occur in the advanced stage.

Also known as: lepromatous leprosy [type L]

3 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Infectious disease (282) Bacterial infectious disease (93) Mycobacterial infectious disease (23) Human disease (14) Leprosy (10) Disease by etiologic mechanism (0) Disease of primarily extrinsic mechanism (0) Primary bacterial infectious disease (0)
Trials to join now! 1 Not yet recruiting 1 Not yet finished but already full! 1
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  • Cheap drug could tame Leprosy's painful Flare-Ups

    Disease control Ongoing

    This study tests whether adding methotrexate to standard steroid treatment can help people with a painful leprosy complication called ENL. 550 adults with active ENL will receive either methotrexate or a placebo alongside prednisolone. The goal is to see if methotrexate reduces t…

    Phase: NA • Sponsor: London School of Hygiene and Tropical Medicine • Aim: Disease control

    Last updated Jun 26, 2026 15:37 UTC

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