Laryngeal disorder
MONDO:0004382A non-neoplastic or neoplastic disorder that affects the larynx. Representative examples include laryngitis, vocal cord polyp, squamous papilloma, and carcinoma.
Also known as: disease of larynx, disease or disorder of larynx, disorder of larynx, disorder of the larynx, laryngeal disease, laryngeal disorder, larynx disease, larynx disease or disorder
237 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
New drug combo aims to stop head and neck cancer relapse in High-Risk patients
Disease control TerminatedThis study tested whether adding the drug xevinapant to standard radiation therapy could help prevent head and neck cancer from coming back after surgery. It included 166 people with high-risk cancer who could not take the usual chemotherapy drug cisplatin. The trial was stopped …
Phase: PHASE3 • Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
-
Experimental drug targets Hard-to-Treat cancers, but trial ends early
Disease control TerminatedThis study tested an experimental drug called vobramitamab duocarmazine in people with advanced prostate cancer and other solid tumors that stopped responding to standard treatments. The goal was to see if the drug could shrink tumors or slow cancer growth. The trial was terminat…
Phase: PHASE2 • Sponsor: MacroGenics • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
-
Common diabetes and acne drugs studied for head and neck cancer treatment
Disease control TerminatedThis study tested whether metformin (a diabetes drug) and doxycycline (an antibiotic) could help treat head and neck cancer when taken before surgery. The trial aimed to see if these drugs could change certain proteins in the tumor's supportive tissue. Only 7 people took part bef…
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
-
Peptide vaccine shows promise in head and neck cancer trial
Disease control TerminatedThis study tested a peptide-based immunotherapy in 17 people with head and neck cancer who were scheduled for surgery. The goal was to see if the vaccine could boost the immune system's attack on cancer cells and to check for side effects. The trial was stopped early, but the res…
Phase: PHASE2 • Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
-
New laryngeal pacemaker aims to restore breathing in vocal cord paralysis
Disease control TerminatedThis study tested a device called the SPIRION Laryngeal Pacemaker in 10 people with bilateral vocal cord paralysis who had prior vocal fold surgery. The device is implanted to help open the vocal cords during breathing. Researchers checked if it was safe and if it improved breath…
Phase: NA • Sponsor: MED-EL Elektromedizinische Geräte GesmbH • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
-
New oxygen device could make throat surgery safer
Symptom relief TerminatedThis study tested a device that delivers high-flow oxygen through the nose during throat surgery. The goal was to keep patients' oxygen levels safe without using a breathing tube. The trial included 29 adults in two French hospitals. The device was considered safe if blood oxygen…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
-
Head and neck cancer drug combo safety trial halted early
Symptom relief TerminatedThis early-phase study aimed to see if adding the drug xevinapant to standard chemoradiotherapy is safe for people with advanced head and neck cancer that cannot be removed by surgery. The study planned to enroll 18 participants but was terminated early. The main focus was on sid…
Phase: PHASE1 • Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
-
Study probes why patients delay throat cancer diagnosis
Knowledge-focused TerminatedThis study looked at why people with mouth or throat cancer wait before seeing a doctor. Researchers interviewed 90 patients and asked them to fill out questionnaires about their feelings, thoughts, and social situation. The goal was to understand what factors cause the delay, so…
Phase: NA • Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC