Irritable bowel syndrome
MONDO:0005052Irritable bowel syndrome (IBS) is a chronic functional condition of the lower gastrointestinal (GI) tract characterized by abdominal pain or discomfort and disordered bowel habit (diarrhea, constipation, or fluctuation between the two).
Also known as: IBS, irritable bowel syndrome, irritable colon, mucus colitis, spastic colon
197 clinical trials for this condition and its sub-types.
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Brain-Targeting drug desipramine tested for IBS pain relief
Symptom relief TerminatedThis study looked at whether desipramine, a medication that affects brain regions involved in pain processing, could help people with irritable bowel syndrome (IBS). Researchers planned to use brain scans to see how the drug changes pain signals in the brain. Only 18 people were …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Shock relief? nerve zaps may ease irritable bowel symptoms
Symptom relief TerminatedThis study looked at whether a treatment called acupuncture-like Transcutaneous Electrical Nerve Stimulation (TENS) could improve quality of life and bowel habits in people with irritable bowel syndrome (IBS). The study planned to enroll 30 adults with IBS, but was terminated ear…
Phase: NA • Sponsor: National Taipei University of Nursing and Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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New drug CIN-103 tested for IBS-D, but trial halted early
Symptom relief TerminatedThis Phase 2 trial tested whether CIN-103, taken twice daily, could ease symptoms of irritable bowel syndrome with diarrhea (IBS-D) in adults. The study planned to enroll 421 participants and compare two doses of CIN-103 against a placebo over 12 weeks. However, the trial was ter…
Phase: PHASE2 • Sponsor: CinPhloro Pharma, LLC • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC