Intracerebral hemorrhage

This study looked at whether adding the drug pioglitazone to a keyhole brain surgery (MIPS) could help people recover from a severe bleeding stroke. Only one person took part before the study was stopped early. The goal was to see if the combination was safe and helped clear the …

This study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…

This study tested a drug called edaravone dexborneol (Sanbexin IV) in 80 people who had a brain bleed (intracerebral hemorrhage). The goal was to see if it is safe and helps recovery when added to standard care. The trial was stopped early, so the results are limited and more res…

This study aimed to see if the antibiotic minocycline could improve outcomes after a stroke. Participants were to receive either standard care plus minocycline pills for five days, or standard care alone. However, the trial was stopped early after enrolling only 2 people, so no m…

This study tested a device called CoolStat that is placed in the nose to cool down brain-injured patients with fever in the ICU. The goal was to see if it could safely and quickly bring their temperature to normal. Only 9 patients were enrolled before the study was stopped early,…

This study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…

This pilot study aimed to see if antiseizure drugs like phenobarbital and levetiracetam change brain connectivity patterns in people with severe acute brain injury and reduced consciousness. Only 5 participants were enrolled before the study was terminated. Researchers used resti…

This study aimed to compare two common sedatives, propofol and midazolam, in patients with traumatic brain injury who needed a breathing tube. Researchers wanted to see if one drug led to better recovery or different levels of inflammation markers called cytokines. However, the t…