Infectious otitis media

This study tested a new vaccine called V114 in over 7,000 healthy infants to see if it could prevent ear infections caused by certain pneumococcal bacteria. The vaccine was given alongside routine childhood shots. Researchers tracked how many babies got vaccine-type ear infection…

This early-stage trial tested whether a new whole-cell pneumonia vaccine is safe for people. Thirty healthy adults received either the vaccine or a placebo and were monitored for 30 days. The main goal was to check for side effects like pain, fever, or headache. This study does n…

This study tested whether analyzing a patient's DNA and RNA could help doctors pick the right drug for inflammatory diseases that don't fit standard categories. 32 adults with at least two affected organs (including skin) received one of six targeted therapies based on their mole…

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…

This study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…

This study tested a low-cost, smartphone-connected device that checks middle ear health. Researchers compared it to standard equipment in 30 adults and children. The goal is to make ear screening affordable and easy for rural communities, reducing preventable hearing loss.

This early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …

This early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…

This study tested whether a low dose of tranexamic acid, a drug that helps blood clot, could reduce bleeding during middle ear surgery. 100 adults undergoing microscopic or endoscopic ear surgery received either the drug or a placebo. The goal was to see if the drug improved the …

This completed study looked at how the social networks of caregivers affect their stress and health when caring for someone with an inherited disease. Researchers surveyed over 680 participants, including family members and formal caregivers, to understand caregiving burden and s…

This study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …

This study tested whether giving doctors automated reports on their antibiotic prescribing habits could improve how often they follow official guidelines. Researchers looked at over 26,000 patients with pneumonia, ear infections, or sore throat. They compared antibiotic use befor…