Infectious otitis media
MONDO:0024330Inflammation of the anatomical structures of the middle ear secondary to an infectious process. Bacterial etiology is most common, but both viral and fungal pathogens are also possible. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever. In severe infections, inflammation and edema of the structures of the middle ear can lead to perforation of the tympanic membrane secondary to the buildup of pressure in the narrow space.
Also known as: otitis media, AOM, acute otitis Media, infectious otitis Media, middle Ear infection
29 clinical trials for this condition and its sub-types.
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New vaccine shows promise against childhood ear infections
⭐️ VACCINE ⭐️ CompletedThis study tested a new vaccine called V114 in over 7,000 healthy infants to see if it could prevent ear infections caused by certain pneumococcal bacteria. The vaccine was given alongside routine childhood shots. Researchers tracked how many babies got vaccine-type ear infection…
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 08:12 UTC
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New pneumonia vaccine passes first safety check in small human trial
⭐️ VACCINE ⭐️ CompletedThis early-stage trial tested whether a new whole-cell pneumonia vaccine is safe for people. Thirty healthy adults received either the vaccine or a placebo and were monitored for 30 days. The main goal was to check for side effects like pain, fever, or headache. This study does n…
Phase: PHASE1 • Sponsor: Serum Life Science Europe GmbH • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 07:55 UTC
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New $50 hearing gadget could bring ear checks to remote villages
Diagnosis CompletedThis study tested a low-cost, smartphone-connected device that checks middle ear health. Researchers compared it to standard equipment in 30 adults and children. The goal is to make ear screening affordable and easy for rural communities, reducing preventable hearing loss.
Sponsor: University of Arkansas • Aim: Diagnosis
Last updated Jun 27, 2026 08:10 UTC
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Can a cheap drug make ear surgery safer and faster?
Symptom relief CompletedThis study tested whether a low dose of tranexamic acid, a drug that helps blood clot, could reduce bleeding during middle ear surgery. 100 adults undergoing microscopic or endoscopic ear surgery received either the drug or a placebo. The goal was to see if the drug improved the …
Phase: NA • Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated Jun 26, 2026 14:29 UTC
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Smart reports guide doctors to better antibiotic choices
Knowledge-focused CompletedThis study tested whether giving doctors automated reports on their antibiotic prescribing habits could improve how often they follow official guidelines. Researchers looked at over 26,000 patients with pneumonia, ear infections, or sore throat. They compared antibiotic use befor…
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC