Infantile apnea

This study tests whether a higher dose of caffeine citrate can improve breathing and reduce complications in extremely premature infants (born before 28 weeks). Forty babies will be randomly assigned to receive either a high or standard dose of caffeine, starting at one week old.…

This trial evaluates a device called BreathAlert, a low-cost, battery-powered monitor designed to detect breathing and alert caregivers when an infant stops breathing (apnea). Researchers are testing it in infants at risk for apnea in a hospital setting, comparing its accuracy to…

This study tests whether giving caffeine citrate to moderately preterm infants for 28 days after hospital discharge can prevent apnea (breathing pauses) that lead to sick visits. About 340 babies in Zambia will receive either caffeine or a placebo daily. Researchers will also che…

This study compares two ways to help extremely premature babies (born at 25-28 weeks) breathe right after birth. One method uses a standard manual T-piece device; the other uses a ventilator to deliver gentle puffs of air through a nasal mask. The goal is to see if the ventilator…

This study tests a medical device called PIMUN to see if it can reduce the time preterm babies spend with low oxygen levels. About 20 infants born before 34 weeks who have apnea of prematurity will be randomly assigned to use the device for 48 hours or receive usual care. Researc…

This trial tests whether button-sized wireless sensors can accurately measure heart rate, oxygen levels, and skin temperature in extremely preterm infants in the NICU. The sensors aim to replace bulky wired monitors that can stress fragile babies. Ten stable preterm infants will …

This study looks at how a pregnant woman's body handles caffeine and how much of it reaches her unborn baby. Researchers will give a small dose of caffeine to 30 women at risk of preterm delivery before a planned C-section. Blood samples from the mother, placenta, and newborn wil…

This study is testing whether a new wireless skin sensor system can safely and accurately monitor the heart rate, breathing, oxygen levels, and temperature of healthy newborns right after birth. 600 babies will wear both the wireless sensors and standard wired monitors for the fi…

This study looks at whether an EEG (a brain wave test) can help doctors know when it's safe to stop giving caffeine to premature babies without their breathing problems coming back. About 100 preterm infants will have an EEG when their caffeine is planned to stop. The goal is to …

This study is testing a small, wireless wearable device that tracks breathing in children. It aims to see if the device works well for kids who have trouble with standard sleep or breathing tests, including premature infants, children with sleep apnea, and those with epilepsy at …

This study looks at whether playing womb-like sounds to preterm infants can help their brains mature and control breathing more steadily. Researchers will monitor 34 babies born at 29-33 weeks for breathing pauses, low oxygen, and slow heart rate. The goal is to understand how ea…