Caffeine trial aims to keep preterm babies breathing safely at home
NCT ID NCT06518603
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving caffeine citrate to moderately preterm infants for 28 days after hospital discharge can prevent apnea (breathing pauses) that lead to sick visits. About 340 babies in Zambia will receive either caffeine or a placebo daily. Researchers will also check if caffeine improves the babies' development at 12 months of age.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
caffeine citrate
What this could lead to
If it works, this could reduce dangerous breathing pauses and emergency visits in preterm babies after they go home, and possibly improve their development at one year.
What could go wrong
This is a Phase 4 trial, but it's still early to know if caffeine helps after discharge. The study is in one country (Zambia), so results may not apply everywhere. Caffeine can cause side effects like jitteriness or fast heart rate.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Teaching Hospital
RECRUITINGLusaka, Lusaka Province, 10100, Zambia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••