Could a muscle relaxant make newborn intubation safer?

NCT ID NCT07650552

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether adding a muscle relaxant (rocuronium) to standard painkiller (fentanyl) helps doctors place breathing tubes in newborns on the first try, without causing dangerous drops in oxygen or heart rate. About 102 premature or sick babies in a Brazilian NICU will take part. The goal is to improve a common procedure that currently fails about half the time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rocuronium (a muscle relaxant) and fentanyl (a painkiller)

What this could lead to

If it works, this could make breathing tube placement safer and more successful for fragile newborns, reducing complications.

What could go wrong

This is a small, early-phase trial (102 babies) in a single hospital, so results may not apply everywhere. Muscle relaxants carry risks like prolonged paralysis, though a reversal drug is available.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Apnea apnea of prematurity newborn respiratory distress syndrome Premature Birth Respiratory Distress Syndrome, Newborn

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Maternidade Ana Braga - UTI Neonatal

    Manaus, Amazonas, 69057000, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••