Could a muscle relaxant make newborn intubation safer?

NCT ID NCT07650552

Not yet recruiting Symptom relief Sponsor: UEA - Universidade Do Estado Do Amazonas Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests whether adding a muscle relaxant (rocuronium) to standard painkiller (fentanyl) helps doctors place breathing tubes in newborns on the first try, without causing dangerous drops in oxygen or heart rate. About 102 premature or sick babies in a Brazilian NICU will take part. The goal is to improve a common procedure that currently fails about half the time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: rocuronium (a muscle relaxant) and fentanyl (a painkiller)
What this could lead to: If it works, this could make breathing tube placement safer and more successful for fragile newborns, reducing complications.
What could go wrong: This is a small, early-phase trial (102 babies) in a single hospital, so results may not apply everywhere. Muscle relaxants carry risks like prolonged paralysis, though a reversal drug is available.

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Conditions

The condition(s) this trial relates to.

Apnea apnea of prematurity newborn respiratory distress syndrome Premature Birth Respiratory Distress Syndrome, Newborn

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APNEA OF PREMATURITY INFANT, PREMATURE INTUBATION, INTRATRACHEAL RESPIRATORY DISTRESS SYNDROME, NEWBORN

Could a muscle relaxant make newborn intubation safer?

Summary

What this could mean

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Conditions

As listed by the trial registrant

Contacts and locations

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