Inclusion body myositis

This study tested a new drug, ABC008, in 272 adults with inclusion body myositis, a rare muscle-weakening disease. The goal was to see if the drug is safe and can help slow the disease's progression. Participants received either ABC008 or a placebo, and their muscle function was …

This study tested whether rapamycin, a drug used in organ transplants, can help people with Inclusion Body Myositis (IBM), a rare muscle disease that causes progressive weakness and has no approved treatment. Forty-four adults with IBM received either rapamycin or a placebo for o…

This study looked at whether whole body MRI can accurately diagnose inflammatory myopathies—a group of muscle diseases causing weakness and damage. Researchers compared MRI results with muscle biopsies in 139 people suspected of having these conditions. If MRI proves reliable, it…

This study tested whether a virtual reality-based robot-assisted exercise program helps people with inflammatory myopathy (a muscle disease causing weakness) more than standard physical therapy. 33 adults trained 5 times a week for 4-6 weeks using either robotic devices or standa…

This study tested whether stem cells taken from a person's own fat tissue are safe to inject into weakened muscles. Nine people with inclusion body myositis received injections in their forearm and thigh. The main goal was to check for side effects, not to measure improvement, th…

This study is building an international registry of people with GNE myopathy, an ultra-rare muscle disease that causes progressive weakness and often leads to wheelchair use. Participants will complete online questionnaires about their symptoms, medical history, quality of life, …

This study investigated whether environmental exposures during military service increase the risk of developing myositis, a rare autoimmune disease that attacks muscles. Researchers compared 37 military personnel with and without myositis using questionnaires and blood samples. N…

This study followed 78 people with GNE myopathy, a rare genetic disease that causes progressive muscle weakness starting in young adulthood. Researchers collected medical history, blood samples, and muscle function tests over up to two years to understand how the disease progress…