New drug shows promise for rare Muscle-Wasting disease
NCT ID NCT05721573
First seen Jan 07, 2026 · Last updated May 14, 2026 · Updated 18 times
Summary
This study tested a new drug called ABC008 in 272 adults with inclusion body myositis, a rare muscle disease that causes weakness. The goal was to see if the drug is safe and can help slow the disease. Participants received either the drug or a placebo, and their muscle function was tracked over time.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AZ Sint-Lucas & Volkskliniek
Ghent, 9000, Belgium
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Austin Neuromuscular Center
Austin, Texas, 78759, United States
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Brigham and Womens Hospital
Boston, Massachusetts, 021158, United States
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Columbia University Medical Center / The Neurological Institute of New York
New York, New York, 10032, United States
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Duke Neurological Disorders Clinic -1L
Durham, North Carolina, 27710, United States
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Genge Partners Inc.
Montreal, Quebec, H4A 3T2, Canada
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Heritage Medical Research Clinic - University of Calgary
Calgary, Alberta, 3M 1M4, Canada
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Hospital Pitie-Salpetriere - AP-HP
Paris, 75013, France
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Hospital for Special Surgery
New York, New York, 10021, United States
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Johns Hopkins Bayview Medical Center
Baltimore, Maryland, 21224, United States
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Johns Hopkins University School of Medicine
Baltimore, Maryland, 21287, United States
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Keck Hosptial of USC
Los Angeles, California, 90033, United States
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Krankenhaus und Poliklinik Rüdersdorf GmbH
Berlin, 15562, Germany
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Mayo Clinic
Jacksonville, Florida, 32224, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Nerve and Muscle Center of Texas
Houston, Texas, 77030, United States
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Neuromuscular Diagnostic Center - Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Neuromuscular Research Center
Phoenix, Arizona, 85028, United States
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Northwestern Memorial Hospital, Department of Neurology (Clinic)
Chicago, Illinois, 60611, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Penn State Health Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
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Perron Institute for Neurological and Translational Science
Nedlands, Western Australia, 6009, Australia
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Royal Brisbane and Women's Hospital
Herston, Queensland, 4006, Australia
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Royal North Shore Hospital
Saint Leonards, New South Wales, 2065, Australia
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Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust
Salford, M6 8HD, United Kingdom
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Stanford Neuroscience Medical Center
Palo Alto, California, 94304, United States
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Texas Neurology
Dallas, Texas, 75206, United States
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The Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
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UCLA Medical Center
Los Angeles, California, 90095, United States
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UPMC Arthritis and Autoimmunity Center, Falk Clinic
Pittsburgh, Pennsylvania, 15213, United States
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University College London Hospitals NHS Foundation Trust, National Hospital for Neurology and Neurosurgery (NHNN)
London, WC1N 3BG, United Kingdom
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University Hosptial Duesseldorf
Düsseldorf, 40225, Germany
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University of California Irvine Medical Center (UCIMC) - Amyotrophic Lateral Sclerosis (ALS) and Neuromuscular Center
Irvine, California, 92868, United States
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University of California, San Francisco
San Francisco, California, 94143, United States
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University of Colorado Hospital Anschutz Outpatient Pavillion
Aurora, Colorado, 80045, United States
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University of Kansas Medical
Kansas City, Kansas, 66160, United States
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University of Nebraska Medical Center
Omaha, Nebraska, 98198, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Washington Medical Center - Montlake
Seattle, Washington, 98195, United States
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Virginia Commonwealth University
Henrico, Virginia, 23233, United States
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Wake Forrest School of Medicine
Winston-Salem, North Carolina, 27157, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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Yale School of Medicine
New Haven, Connecticut, 06519, United States
Conditions
Explore the condition pages connected to this study.