Hypothyroidism

This study tests whether a smartphone app and text reminders can help people with hypothyroidism take their thyroid medication more regularly. The goal is to see if better medication adherence reduces fatigue, helps with weight management, and improves thyroid hormone levels. The…

This study will test whether a special MRI technique called T1 mapping can find and measure tiny scars in the heart muscle of people with long-term thyroid disease. The goal is to see if this non-invasive scan can replace the need for a heart biopsy. The study plans to enroll 40 …

This phase 2 trial tests a dye called bevonescein that makes nerves glow during thyroid surgery, helping surgeons see and avoid them. Forty adults having thyroid removal will receive the dye before surgery. The main goal is to see if it improves voice outcomes by reducing nerve i…

This study tests whether adding a second thyroid hormone (T3) to the standard T4 treatment can improve persistent symptoms like fatigue and brain fog in people with hypothyroidism. It involves 60 adults aged 18-70 who still have symptoms despite normal thyroid blood tests. Partic…

This study compares two tools used during thyroid removal surgery: LigaSure and bipolar diathermy. The goal is to see which one leads to shorter surgery time, less pain, and fewer complications. Thirty adults having partial or total thyroid removal will take part.

This study tests whether a structured 12-week walking program can improve metabolism, reduce fatigue, and lower stress in women with hypothyroidism who are already on thyroid medication. 120 women aged 35-55 will either walk 30 minutes, 5 times a week under supervision, or contin…

This study tests a computer vision model called PTAIR that helps surgeons identify parathyroid glands and recurrent laryngeal nerves during endoscopic thyroid surgery. About 100 adults with thyroid disease will take part. The model's ability to spot these structures will be compa…

This study will measure how much of the pesticide chlordecone is stored in the thyroid and nearby fat tissue of 69 adults having thyroid surgery in Guadeloupe. Researchers will also look at blood levels and ask about diet and job history to see what factors affect accumulation. T…

This study will check if doing two blood tests instead of one can better detect congenital hypothyroidism in premature babies born before 32 weeks. Researchers will follow 1,600 newborns in France, testing them within 15 days of birth and again at 2 years if needed. The goal is t…

This study will use ultrasound to measure the thyroid gland in 400 healthy full-term newborns in Italy. The goal is to create a set of normal thyroid volume values, which currently do not exist for this population. These reference values can help doctors better diagnose thyroid p…

This study looks at whether a mild form of underactive thyroid (subclinical hypothyroidism) affects liver enzymes and cholesterol levels. Researchers will compare 120 adults with and without the condition. No treatment is given — the goal is simply to understand the connection be…