Could adding T3 to standard thyroid treatment ease persistent symptoms?
NCT ID NCT07424183
First seen Feb 28, 2026 · Last updated May 24, 2026 · Updated 11 times
Summary
This study tests whether adding a second thyroid hormone (T3) to the standard T4 medication can improve lingering symptoms like fatigue and brain fog in people with hypothyroidism. About 60 adults aged 18-70 with normal thyroid blood tests but ongoing symptoms will receive either T4 plus T3 or T4 plus a placebo for 6 months. The goal is to see if the combination therapy leads to better quality of life.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Penn Medicine, Smilow Center for Translational Resarch,
Philadelphia, Pennsylvania, 19104, United States
Conditions
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