Could a second thyroid hormone end lingering fatigue?
NCT ID NCT07424183
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a second thyroid hormone (T3) to the standard T4 treatment can improve persistent symptoms like fatigue and brain fog in people with hypothyroidism. It involves 60 adults aged 18-70 who still have symptoms despite normal thyroid blood tests. Participants will receive either T4 plus T3 or T4 plus a placebo for 6 months, and their quality of life and symptom changes will be measured.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Penn Medicine, Smilow Center for Translational Resarch,
Philadelphia, Pennsylvania, 19104, United States
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