Hypothalamic disorder
MONDO:0002150Neoplastic, inflammatory, infectious, and other diseases of the hypothalamus. Clinical manifestations include appetite disorders; autonomic nervous system diseases; sleep disorders; behavioral symptoms related to dysfunction of the limbic system; and neuroendocrine disorders.
Also known as: disease of hypothalamus, disease or disorder of hypothalamus, disorder of hypothalamus, hypothalamus disease, hypothalamus disease or disorder
87 clinical trials for this condition and its sub-types.
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Broader categories
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Chemotherapy drug temozolomide under review for tough pituitary tumors
Disease control Not yet recruitingThis study looks at how well the chemotherapy drug temozolomide works for people with aggressive pituitary tumors or pituitary cancer that hasn't responded to standard treatments like surgery or radiation. Researchers are collecting data from medical records across multiple hospi…
Sponsor: University of Sao Paulo General Hospital • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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A simple eye-tracking test may replace button-pressing exams for pituitary tumor patients
Diagnosis Not yet recruitingThis study tests whether a new eye-tracking device called SONDA can accurately measure visual field loss in people with pituitary tumors. Standard visual field tests require patients to press a button when they see lights, which can be tiring and unreliable. The SONDA test instea…
Sponsor: University Medical Center Groningen • Aim: Diagnosis
Last updated Jul 25, 2026 00:00 UTC
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New scan could spot invisible brain tumors
Diagnosis Not yet recruitingThis study tests whether a special PET scan (18FET) can find small pituitary tumors that standard MRI scans miss. About 30 adults with suspected hormone-secreting pituitary tumors will receive the scan. If it works, it could help doctors decide on surgery or radiation without nee…
Phase 2 • Sponsor: University Hospital, Lille • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Brain surgery safety: live signal monitoring may shield speech, movement, and sight
Knowledge-focused Not yet recruitingResearchers at Odense University Hospital are testing whether monitoring brain signals during tumor surgery can help preserve functions like movement, speech, and vision. The project includes a randomized trial comparing surgery with and without motor signal monitoring, plus obse…
Sponsor: Odense University Hospital • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Can a Nose-Route surgery remove skull base tumors more safely?
Knowledge-focused Not yet recruitingThis study looks at a surgical technique called the extended endoscopic endonasal approach (EEEA), which removes skull base lesions through the nose. The goal is to see how completely the tumor can be removed and how safe the procedure is. Adults with certain skull base tumors, s…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Which intubation method works best for acromegaly patients?
Knowledge-focused Not yet recruitingThis study looks at how to safely place a breathing tube in people with acromegaly, a condition that can cause changes in the face and airway. It compares two methods: direct laryngoscopy and video laryngoscopy. The goal is to find which method gives a better view of the airway a…
Sponsor: Muzaffer GENCER • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Patient education may shorten hospital stays after pituitary surgery
Knowledge-focused Not yet recruitingThis study looks at whether giving patients clear, standardized instructions before and after pituitary surgery can improve their recovery. Researchers will compare hospital stay length, complication rates, and unplanned readmissions in 102 adults having elective surgery. The goa…
Sponsor: Uludag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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AI assistant for brain tumor surgery: a new training tool?
Knowledge-focused Not yet recruitingThis early-phase trial tests an artificial intelligence system that watches live video from pituitary tumor surgeries performed through the nose. The AI identifies anatomy, instruments, and surgical steps, displaying its analysis on tablets for the surgical team (not the lead sur…
Early phase 1 • Sponsor: University College, London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Treatment strategies for tumor in sellar region with unruptured intracranial aneurysms in the chinese population
Not yet recruitingThe goal of this observational study is to learn about the treatment strategies for tumor in sellar region with unruptured intracranial aneurysms in the Chinese population. The main question it aims to answer is: For patients with tumor in sellar region combined with unruptured i…
Sponsor: Cheng sen
Last updated Sep 09, 2026 17:58 UTC