Chemotherapy drug temozolomide under review for tough pituitary tumors
NCT ID NCT07695844
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This study looks at how well the chemotherapy drug temozolomide works for people with aggressive pituitary tumors or pituitary cancer that hasn't responded to standard treatments like surgery or radiation. Researchers are collecting data from medical records across multiple hospitals in Latin America to see how patients respond, how long the tumor is controlled, and whether certain tumor features can predict who benefits most. The goal is to fill a gap in knowledge, since most existing data comes from Europe and the United States.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- temozolomide (chemotherapy drug)
- What this could lead to
- If results are positive, this could confirm temozolomide as a reliable treatment option for aggressive pituitary tumors in Latin America.
- What could go wrong
- This is a retrospective study, not a controlled trial, so results may be less reliable. Temozolomide can cause side effects like nausea, fatigue, and low blood cell counts.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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- New scan could spot pituitary tumors more clearly