Hyperthyroidism

This study tested an investigational drug called VRDN-001 in 143 people with thyroid eye disease who did not improve in earlier studies. The drug aims to reduce inflammation and eye bulging by blocking a specific receptor. Researchers measured how many participants had at least a…

This Phase 3 trial tested an investigational drug called veligrotug (VRDN-001) in 188 people with chronic thyroid eye disease. The drug is an antibody that blocks a protein involved in the disease. The main goal was to see if it could reduce eye bulging (proptosis) compared to a …

This study tested a drug called batoclimab in 35 adults with Graves' disease whose thyroid hormone levels were still high despite taking standard antithyroid drugs. The goal was to see if batoclimab could help bring those levels back to normal or below over 24 weeks. Batoclimab w…

This completed Phase 3 trial tested a drug called VRDN-001 in 231 people with thyroid eye disease (TED). The drug works by blocking a receptor involved in inflammation and swelling. The main goal was to check safety and tolerability, with secondary goals including measuring chang…

This trial tests whether veligrotug, an antibody that blocks a receptor involved in inflammation, can reduce eye bulging and swelling in people with active thyroid eye disease. Participants receive five infusions of the drug or a placebo. The study measures how many people see a …

This study tests whether a simple foot exercise called the soleus pushup can improve cholesterol, blood sugar, and hormone levels in people with thyroid problems, high blood pressure, or diabetes. Participants will perform the exercise, and researchers will measure changes in blo…

This study looked at whether a tea made from wild blackberry root could improve thyroid health in people with Graves' disease, an autoimmune condition that causes an overactive thyroid. Forty-two adults with newly diagnosed or relapsed Graves' disease drank either the blackberry …

This study looked at whether tocilizumab, a drug that calms the immune system, can help people with active moderate-to-severe thyroid eye disease that did not get better with steroids. Thirty-two adults received the drug every four weeks. Researchers measured improvements in eye …

This study tested whether wearing virtual reality glasses during a fine needle biopsy of the thyroid could lower stress and pain in people with hyperthyroidism. 52 patients took part. Researchers measured stress and pain levels using questionnaires and checked vital signs. The go…

This study compared two types of thyroid surgery: one using a microscope and the standard approach. Researchers looked at blood loss, nerve damage, and low calcium levels after surgery in 74 patients with thyroid cancer or other thyroid conditions. The goal was to see if the micr…

This study tested whether doing gentle neck exercises for 10 days after thyroid surgery could reduce pain and improve quality of life. 93 adults who had their thyroid removed were split into two groups: one did the exercises, the other received standard care. Researchers measured…

This study tested whether adding dexmedetomidine to a standard nerve block (superficial cervical plexus block) improves pain control after thyroid surgery. Fifty-eight adults undergoing thyroid surgery were randomly assigned to receive the nerve block with or without dexmedetomid…

This completed study from Minia University looked at 200 patients with autoimmune thyroiditis (an inflamed thyroid) who had thyroid surgery. The goal was to see how often thyroid cancer is found by accident when examining the removed tissue. Researchers checked for cancer in pati…

This study investigates whether measuring ionized calcium levels before, during, and after total thyroidectomy can predict which patients will develop low calcium levels (hypocalcemia) after surgery. Researchers will track calcium and parathyroid hormone levels in 327 adults unde…

This study tested whether a newer 3D imaging method (SPECT/CT) is as accurate as the standard 2D method for measuring how much the thyroid gland takes up a radioactive tracer. 27 people with underactive or overactive thyroids were scanned with both methods. The goal was to see if…

This study looked at whether specially engineered versions of a natural immune protein (IL-2) can selectively boost regulatory T cells, which help calm the immune system. Researchers took blood samples from 67 people with various autoimmune or inflammatory conditions and tested t…

This study tested whether a parvovirus infection might trigger Graves' disease, an autoimmune condition affecting the thyroid. Researchers compared 52 people—half recently diagnosed with Graves' disease and half with thyroid nodules or goiter—by checking their blood for parvoviru…