Hereditary motor neuron disease

MONDO:0024257

An instance of motor neuron disease that is caused by an inherited modification of the individual's genome.

Also known as: genetic anterior horn cell disease, genetic motor neuron disease, hereditary motor neuron disease

176 clinical trials for this condition and its sub-types, 1 tagged with Hereditary motor neuron disease itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Hereditary neuromuscular disease (932) ↑ Inherited neurodegenerative disorder (807) ↑ Motor neuron disorder (506)

Sub-types of Hereditary motor neuron disease

Spinal muscular atrophy 107 trials · 117 incl. sub-types
19 sub-types
- Proximal spinal muscular atrophy 14 trials · 42 incl. sub-types Sub-types →
- Autosomal recessive distal spinal muscular atrophy 1 2 trials
- Bulbospinal muscular atrophy 1 trial Sub-types →
- X-linked distal spinal muscular atrophy type 3 0 trials
- Adult-onset proximal spinal muscular atrophy, autosomal dominant 0 trials
- Autosomal recessive distal spinal muscular atrophy 2 0 trials
- Infantile-onset X-linked spinal muscular atrophy 0 trials
- Neuronopathy, distal hereditary motor, autosomal dominant 0 trials Sub-types →
- Neuronopathy, distal hereditary motor, autosomal recessive 3 0 trials
- Neuronopathy, distal hereditary motor, autosomal recessive 4 0 trials
- Neuronopathy, distal hereditary motor, autosomal recessive 5 0 trials
- Scapuloperoneal spinal muscular atrophy, autosomal dominant 0 trials
- Scapuloperoneal spinal muscular atrophy, autosomal recessive 0 trials
- Spinal muscular atrophy type 0 0 trials
- Spinal muscular atrophy with respiratory distress type 2 0 trials
- Spinal muscular atrophy, Ryukyuan type 0 trials
- Spinal muscular atrophy, facioscapulohumeral type 0 trials
- Spinal muscular atrophy, segmental 0 trials
- Spinal muscular atrophy-progressive myoclonic epilepsy syndrome 0 trials
Familial amyotrophic lateral sclerosis 2 trials · 29 incl. sub-types
30 sub-types
- Spinocerebellar ataxia type 2 10 trials Sub-types →
- Amyotrophic lateral sclerosis type 1 8 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 1 5 trials
- Amyotrophic lateral sclerosis type 10 3 trials
- Amyotrophic lateral sclerosis type 4 1 trial
- Amyotrophic lateral sclerosis type 6 1 trial
- Amyotrophic lateral sclerosis type 7 1 trial
- Amyotrophic lateral sclerosis 26 with or without frontotemporal dementia 0 trials
- Amyotrophic lateral sclerosis 27, juvenile 0 trials
- Amyotrophic lateral sclerosis 28 0 trials
- Amyotrophic lateral sclerosis type 11 0 trials
- Amyotrophic lateral sclerosis type 12 0 trials
- Amyotrophic lateral sclerosis type 15 0 trials
- Amyotrophic lateral sclerosis type 18 0 trials
- Amyotrophic lateral sclerosis type 19 0 trials
- Amyotrophic lateral sclerosis type 20 0 trials
- Amyotrophic lateral sclerosis type 21 0 trials
- Amyotrophic lateral sclerosis type 22 0 trials
- Amyotrophic lateral sclerosis type 23 0 trials
- Amyotrophic lateral sclerosis type 3 0 trials
- Amyotrophic lateral sclerosis type 8 0 trials
- Amyotrophic lateral sclerosis type 9 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 2 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 3 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 4 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 5 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 6 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 7 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 8 0 trials
- Juvenile amyotrophic lateral sclerosis 0 trials Sub-types →
Lateral sclerosis 24 trials
2 sub-types
- Primary lateral sclerosis, adult, 1 1 trial
- Juvenile primary lateral sclerosis 0 trials
Riboflavin transporter deficiency 1 trial · 6 incl. sub-types
3 sub-types
- Progressive bulbar palsy 5 trials Sub-types →
- Brown-Vialetto-van Laere syndrome 1 0 trials
- Brown-Vialetto-van Laere syndrome 2 0 trials
Distal hereditary motor neuropathy 0 trials · 4 incl. sub-types
3 sub-types
- Neuronopathy, distal hereditary motor, autosomal recessive 0 trials · 4 incl. sub-types Sub-types →
- X-linked distal spinal muscular atrophy type 3 0 trials
- Neuronopathy, distal hereditary motor, autosomal dominant 0 trials Sub-types →
ALS2-related motor neuron disease 0 trials
3 sub-types
- Amyotrophic lateral sclerosis type 2, juvenile 0 trials
- Infantile-onset ascending hereditary spastic paralysis 0 trials
- Juvenile primary lateral sclerosis 0 trials
Motor neuron disease with dementia and ophthalmoplegia 0 trials
Neurogenic scapuloperoneal syndrome, Kaeser type 0 trials
Prenatal-onset spinal muscular atrophy with congenital bone fractures 0 trials
2 sub-types
- Spinal muscular atrophy with congenital bone fractures 1 0 trials
- Spinal muscular atrophy with congenital bone fractures 2 0 trials

Most studied deeper sub-types

Spinal muscular atrophy, type 1 (17) Spinal muscular atrophy, type II (14) Spinal muscular atrophy, type III (13) Neuronopathy, distal hereditary motor, autosomal recessive 8 (2) Spinal muscular atrophy, type IV (2) Amyotrophic lateral sclerosis type 16 (0) Amyotrophic lateral sclerosis type 5 (0) Autosomal dominant childhood-onset proximal spinal muscular atrophy (0) Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures (0) Autosomal dominant childhood-onset proximal spinal muscular atrophy without contractures (0) COQ7-related distal hereditary motor neuropathy (0) Distal hereditary motor neuropathy type 2 (0) Distal hereditary motor neuropathy type 7 (0) Early-onset progressive encephalopathy-spastic ataxia-distal spinal muscular atrophy syndrome (0) Hereditary spastic paraplegia 17 (0) Juvenile amyotrophic lateral sclerosis with dementia (0) Lower motor neuron syndrome with late-adult onset (0) Myopathy, myofibrillar, 13, with rimmed vacuoles (0) Neuronopathy, distal hereditary motor, autosomal dominant 1 (0) Neuronopathy, distal hereditary motor, autosomal dominant 10 (0)

Including sub-types (176) Tagged with Hereditary motor neuron disease (1)

Trials to join now! 65 Not yet recruiting 11 Not yet finished but already full! 50 Completed 46 Terminated 4

Hereditary motor neuron disease

Where it sits in the disease tree

Most studied deeper sub-types

Can gene therapy help babies with SMA reach milestones? a Real-World review

Could stem cells help people with spinocerebellar ataxia? new trial aims to find out

Robot leg training tuned to each child may build stronger knees in SMA

Can a support group boost confidence for parents of kids with DMD or SMA?

Horse power: new therapy hopes to improve movement in SMA children

Robot suit aims to get kids with disabilities walking

Can gene therapy zolgensma safely improve motor skills in SMA?

School transitions put to the test for children with a rare muscle disease

New study explores how families cope with feeding and talking challenges in SMA type 1

Hidden fracture risk in kids with SMA under spotlight

New study probes emotional toll of SMA screening on new parents