Could stem cells help people with spinocerebellar ataxia? new trial aims to find out

NCT ID NCT03378414

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests whether umbilical cord stem cells can safely improve movement and coordination in people with spinocerebellar ataxia (types 1, 2, 3, and 6). Forty-five participants will receive the cells through an IV and a spinal injection. The main goal is to see if symptoms get better after 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

umbilical cord mesenchymal stem cells

What this could lead to

If this works, it could point toward a treatment that slows or partially reverses movement problems in certain types of spinocerebellar ataxia.

What could go wrong

This is a small, early Phase 2 trial with only 45 people. The stem cells may not improve symptoms, and there are risks from the infusion and injection procedures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Machado-Joseph disease spinocerebellar ataxia type 1 spinocerebellar ataxia type 2 spinocerebellar ataxia type 6 Spinocerebellar Ataxias

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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