Hereditary glaucoma
MONDO:0018174Hereditary glaucoma is a clinically diverse group of rare eye disorders with genetic predisposition characterized by elevated intraocular pressure (IOP) and glaucomatous changes of the optic nerve head, leading to field defects, visual loss and blindness. Hereditary glaucoma can be sub-classified as primary (congenital glaucoma, juvenile glaucoma) or secondary according to the presence or absence of systemic or other ocular anomalies (iridogoniodysgenesis, Stickler syndrome, Coats syndrome). The clinical presentation is variable and is based on age, severity of glaucoma, presence of ocular abnormalities and development of secondary IOP related abnormalities.
Also known as: hereditary glaucoma (disease), glaucoma, hereditary
56 clinical trials for this condition and its sub-types, 0 tagged with Hereditary glaucoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hereditary glaucoma
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Exfoliation syndrome 32 trials
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Juvenile open angle glaucoma 7 trials · 15 incl. sub-types
6 sub-types
- Glaucoma 1, open angle, l 8 trials
- Glaucoma 1, open angle, A 0 trials
- Glaucoma 1, open angle, J 0 trials
- Glaucoma 1, open angle, K 0 trials
- Glaucoma 1, open angle, M 0 trials
- Glaucoma 1, open angle, N 0 trials
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Congenital glaucoma 7 trials · 8 incl. sub-types
4 sub-types
- Primary congenital glaucoma 3 trials · 5 incl. sub-types Sub-types →
- Glaucoma 3, primary congenital, E 0 trials
- Glaucoma 3, primary infantile, B 0 trials
- Glaucoma type 1C 0 trials
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Anterior segment dysgenesis 3 1 trial
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Iris hypoplasia with glaucoma 1 trial
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OPTN-related open angle glaucoma 0 trials
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TEK-related primary glaucoma 0 trials
1 sub-type
- Glaucoma 3, primary congenital, E 0 trials
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Glaucoma 1, open angle, O 0 trials
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Glaucoma 1, open angle, P 0 trials
Most studied deeper sub-types
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New laser method could make glaucoma treatment easier
Disease control By invitation onlyThis study tests if a new, automated laser treatment (DSLT) works as well as the standard laser treatment (SLT) for lowering eye pressure in people with open-angle glaucoma. About 51 adults will receive one of the two treatments and be followed for 12 months. The goal is to see i…
Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Laser showdown: which glaucoma protocol wins?
Disease control OngoingThis study compares different ways of performing a laser treatment called selective laser trabeculoplasty (SLT) for people with open-angle glaucoma or high eye pressure. 400 participants will receive SLT using one of several protocols, and researchers will track how much their ey…
Sponsor: Vastra Gotaland Region • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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Can Vitamin-Like supplements save sight in glaucoma?
Disease control OngoingThis study tests whether taking nicotinamide and pyruvate supplements can help protect the eyes of people with open-angle glaucoma. About 250 adults aged 35 to 85 will take either the supplements or a placebo for 20 months, while continuing their standard glaucoma medications. Th…
Phase 2/3 • Sponsor: Columbia University • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New eye implant aims to ease glaucoma pressure
Disease control OngoingThis study tests a small implant placed inside the eye to help drain fluid and lower pressure in people with open-angle or narrow-angle glaucoma. It is for adults whose eye pressure is not well controlled with eye drops. The main goal is to see if the implant safely reduces press…
Sponsor: Ciliatech • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Tiny implant could ease glaucoma pressure
Disease control OngoingThis study tests a new device called the VividWhite Glaucoma Implant, which is surgically placed in the eye to help lower pressure in people with glaucoma. Sixty-five participants will be followed for 12 months to see if the implant safely reduces eye pressure and lessens the nee…
Sponsor: VividWhite Pty Ltd • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Tiny steroid implant may boost glaucoma surgery success
Disease control OngoingThis pilot study tests whether placing a slow-release steroid insert (Yutiq) during glaucoma drainage surgery helps reduce scarring and keeps eye pressure lower. About 5 adults with glaucoma will receive the implant along with their surgery. Researchers will compare their pressur…
Early phase 1 • Sponsor: Sanjay Asrani • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Can repeat laser eye treatment keep glaucoma in check?
Disease control By invitation onlyThis study looks at the best way to repeat a laser treatment called SLT for people with open-angle glaucoma or high eye pressure. Researchers will compare different treatment methods in 400 participants who were already in an earlier SLT trial. The goal is to see how well repeat …
Sponsor: Vastra Gotaland Region • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Eye fluid analysis may unlock secrets of rare eye condition
Knowledge-focused OngoingThis pilot study examines proteins in the vitreous (the gel-like fluid inside the eye) of patients with pseudoexfoliation syndrome (PEX), a condition that can lead to glaucoma. Researchers will compare protein levels between eyes with and without PEX in 24 adults undergoing eye s…
Sponsor: Prim. Prof. Dr. Oliver Findl, MBA • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC