Can Vitamin-Like supplements save sight in glaucoma?
NCT ID NCT05695027
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking nicotinamide and pyruvate supplements can help protect the eyes of people with open-angle glaucoma. About 250 adults aged 35 to 85 will take either the supplements or a placebo for 20 months, while continuing their standard glaucoma medications. The goal is to see if the supplements slow damage to the optic nerve and preserve vision.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nicotinamide and pyruvate (dietary supplements)
What this could lead to
If it works, this could offer a simple, safe supplement to help preserve vision in people with glaucoma.
What could go wrong
This is a mid-stage trial with 250 participants, so results may not apply to everyone. Supplements may not slow vision loss beyond standard care.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Columbia University Irving Medical Center - 622 W 168th St
New York, New York, 10032, United States
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ColumbiaDoctors Ophthalmology - 880 Third Avenue
New York, New York, 10022, United States
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Stanford University Department of Ophthalmology
Palo Alto, California, 94303, United States