Hereditary glaucoma

This study tests whether removing the ripcord from a glaucoma drainage device more than 3 months after placement lowers eye pressure. Adults with glaucoma who have had the ripcord in place for over 3 months will have it removed during a routine clinic visit. Researchers will meas…

This trial tests a new device called VividFlo, a small implant placed under the eye's surface to help drain fluid and lower pressure in people with glaucoma. The study involves 10 adults with glaucoma in one eye, who will receive the implant during surgery. Researchers will track…

This trial compares two surgical implants—the Baerveldt Glaucoma Implant and the Paul Glaucoma Implant—in people with glaucoma that is not well controlled by eye drops. Both devices are tiny tubes placed in the eye to drain fluid and lower pressure. The study will track which imp…

This trial investigates whether a 12-week home-based circuit training program can reduce intraocular pressure and improve retinal health in people with glaucoma. Participants are randomly assigned to either the exercise program plus standard care or standard care alone. The study…

This study tests whether insulin eye drops can protect the optic nerve in people with open-angle glaucoma. Researchers will give 90 participants either insulin drops or placebo daily for up to 12 months. The main goal is to check safety, but they will also measure vision changes …

This study looks at children with a rare, severe eye disease called primary congenital glaucoma. It compares three different amounts of a surgery called goniotomy (120°, 240°, or 360°) to see which works best and is safest. The goal is to lower eye pressure and protect vision, bu…

This study tests whether placing a temporary stitch inside a tiny drainage device (Preserflo) can reduce the risk of dangerously low eye pressure after glaucoma surgery. The device is already used in France to lower eye pressure, but low pressure can still happen. About 192 adult…

This study tests a non-invasive laser procedure called direct selective laser trabeculoplasty (DSLT) in 40 adults with pseudoexfoliation glaucoma. The goal is to see if the laser can safely lower eye pressure by at least 20% at 6 and 12 months. Participants will have their eye pr…

This trial tests whether a structured reading rehabilitation module can improve reading speed and reduce errors in people with glaucoma, a condition that often impairs vision. Participants will practice the module for 20-30 minutes daily, at least 3 days a week, for 6 months. The…

This study will test whether a special type of lens implant (extended depth-of-focus, or EDOF) can give better vision and more satisfaction than standard monofocal lenses for people with both glaucoma and cataracts. About 74 adults with early-to-moderate open-angle glaucoma will …

This study follows 70 adults aged 50 and older who are having routine cataract surgery. Half have pseudoexfoliation syndrome, a condition that can weaken eye tissues, and half do not. Researchers measure corneal stiffness before surgery and at several points afterward to see whet…

This study looks at whether a common type of glaucoma eye drop (prostaglandin analogues) can protect the eye's nerve cells directly, not just by lowering eye pressure. Researchers will review medical records from 1500 adults with glaucoma over 3 years, comparing those on prostagl…

This study looks at how different ways of managing a child's airway during anesthesia affect eye pressure and heart rate in children having surgery for congenital glaucoma. 75 children will be split into three groups, each receiving a different airway device. The goal is to find …