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Hereditary glaucoma
MONDO:0018174Hereditary glaucoma is a clinically diverse group of rare eye disorders with genetic predisposition characterized by elevated intraocular pressure (IOP) and glaucomatous changes of the optic nerve head, leading to field defects, visual loss and blindness. Hereditary glaucoma can be sub-classified as primary (congenital glaucoma, juvenile glaucoma) or secondary according to the presence or absence of systemic or other ocular anomalies (iridogoniodysgenesis, Stickler syndrome, Coats syndrome). The clinical presentation is variable and is based on age, severity of glaucoma, presence of ocular abnormalities and development of secondary IOP related abnormalities.
Also known as: hereditary glaucoma (disease), glaucoma, hereditary
51 clinical trials for this condition and its sub-types.
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Broader categories
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Could insulin eye drops save your sight? new trial launches
Disease control Not yet recruitingThis study tests whether insulin eye drops can protect the optic nerve in people with open-angle glaucoma. Researchers will give 90 participants either insulin drops or placebo daily for up to 12 months. The main goal is to check safety, but they will also measure vision changes …
Phase: PHASE1, PHASE2 • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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How much eye surgery is best for babies with glaucoma?
Disease control Not yet recruitingThis study looks at children with a rare, severe eye disease called primary congenital glaucoma. It compares three different amounts of a surgery called goniotomy (120°, 240°, or 360°) to see which works best and is safest. The goal is to lower eye pressure and protect vision, bu…
Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New stitch technique aims to prevent dangerous low eye pressure after glaucoma surgery
Disease control Not yet recruitingThis study tests whether placing a temporary stitch inside a tiny drainage device (Preserflo) can reduce the risk of dangerously low eye pressure after glaucoma surgery. The device is already used in France to lower eye pressure, but low pressure can still happen. About 192 adult…
Phase: NA • Sponsor: Hôpital Privé de la Baie • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Laser procedure could offer new hope for pseudoexfoliation glaucoma patients
Disease control Not yet recruitingThis study tests a non-invasive laser procedure called direct selective laser trabeculoplasty (DSLT) in 40 adults with pseudoexfoliation glaucoma. The goal is to see if the laser can safely lower eye pressure by at least 20% at 6 and 12 months. Participants will have their eye pr…
Phase: NA • Sponsor: Vance Thompson Vision • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New lens option may reduce need for glasses after cataract surgery in glaucoma patients
Symptom relief Not yet recruitingThis study will test whether a special type of lens implant (extended depth-of-focus, or EDOF) can give better vision and more satisfaction than standard monofocal lenses for people with both glaucoma and cataracts. About 74 adults with early-to-moderate open-angle glaucoma will …
Phase: NA • Sponsor: OMIQ Research • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Eye drop showdown: could common glaucoma meds save more than sight?
Knowledge-focused Not yet recruitingThis study looks at whether a common type of glaucoma eye drop (prostaglandin analogues) can protect the eye's nerve cells directly, not just by lowering eye pressure. Researchers will review medical records from 1500 adults with glaucoma over 3 years, comparing those on prostagl…
Sponsor: Association for Innovation and Biomedical Research on Light and Image • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New study tests best breathing tube for Kids' eye surgery
Knowledge-focused Not yet recruitingThis study looks at how different ways of managing a child's airway during anesthesia affect eye pressure and heart rate in children having surgery for congenital glaucoma. 75 children will be split into three groups, each receiving a different airway device. The goal is to find …
Phase: NA • Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC