Laser showdown: which glaucoma protocol wins?

NCT ID NCT03798223

Ongoing Disease control Sponsor: Vastra Gotaland Region Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This study compares different ways of performing a laser treatment called selective laser trabeculoplasty (SLT) for people with open-angle glaucoma or high eye pressure. 400 participants will receive SLT using one of several protocols, and researchers will track how much their eye pressure drops over three years. The goal is to find the safest and most effective approach to lower eye pressure and possibly delay the need for eye drops or surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Selective laser trabeculoplasty (SLT) with pilocarpine and tetracaine eye drops
What this could lead to: If successful, this could establish a standard, more effective laser procedure to lower eye pressure and reduce the need for daily eye drops in glaucoma patients.
What could go wrong: This is a mid-stage trial comparing different laser techniques, not testing a new drug. The results may show only modest differences between protocols, and long-term effectiveness varies by patient.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

exfoliation syndrome ocular hypertension open-angle glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLAUCOMA, OPEN-ANGLE OCULAR HYPERTENSION PSEUDOEXFOLIATION GLAUCOMA

Contacts and locations

Locations

Ogonkliniken NU-sjukvarden

Uddevalla, Västra Götaland County, 45153, Sweden
Ogonkliniken, Sahlgrenska Universitetssjukhuset

Mölndal, Västra Götaland County, 43130, Sweden
Ogonkliniken, Skaraborgs Sjukhus

Skövde, Västra Götaland County, 54142, Sweden
Ogonkliniken, Sodra Alvsborgs Sjukhus

Borås, Västra Götaland County, 50182, Sweden

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