Hemicrania continua
MONDO:0018615Hemicrania continua (HC) is a type of primary headache disorder, which means the headache is not caused by another medical condition. Symptoms of HC include constant mild to moderate pain on one side of the head (unilateral) with periods of more intense, severe, migraine -like pain (exacerbations). These severe pain periods can last from 20 minutes to days. The frequency of exacerbations also varies greatly. The headache stays on the same side of the head and usually without pain free periods. HC is more common in women and most often starts in adulthood, but may begin anywhere from 5 to 67 years of age. Diagnosis of hemicrania continua (HC) is made by ruling out other possible causes of the pain and by clinical symptoms. During the periods of severe pain, at least one of the following symptoms must be present on same side of the body as the headache: watering or red eyes (conjunctival injection), congested or runny nose, or drooping eyelid. In addition, the headache pain must respond to treatment with indomethacin. The cause of HC is unknown. Other treatments for those who cannot tolerate long term indomethacin therapy are being studied.
12 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
ER headache relief: could a steroid combo beat standard painkillers?
Symptom relief Not yet recruitingThis study compares a combination of two drugs (dexamethasone and metoclopramide) against standard painkillers (paracetamol or NSAIDs) for treating severe primary headaches in the emergency department. 94 adults aged 18-60 with a pain score of 5 or higher will be randomly assigne…
Phase: PHASE4 • Sponsor: Pak Emirates Military Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
-
Teen headache mystery: could uric acid be a clue?
Knowledge-focused Not yet recruitingThis study compares uric acid levels in 80 adolescents (12-18 years) with and without primary headaches. Researchers aim to see if there is a link between uric acid and headaches, which could help understand what causes them. Participants will provide a blood sample and have thei…
Sponsor: Konya Necmettin Erbakan Üniversitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC