ER headache relief: could a steroid combo beat standard painkillers?
NCT ID NCT07605065
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a combination of two drugs (dexamethasone and metoclopramide) against standard painkillers (paracetamol or NSAIDs) for treating severe primary headaches in the emergency department. 94 adults aged 18-60 with a pain score of 5 or higher will be randomly assigned to one of the two treatments. The goal is to see which approach provides faster and more effective pain relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexamethasone plus metoclopramide (given intravenously)
What this could lead to
If it works, this could offer a faster, more effective way to relieve severe headaches in the emergency room.
What could go wrong
This is a small, single-hospital trial (94 people) and may not apply to all headache types. Side effects from the drugs are possible.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PRIMARY HEADACHE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••