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Generalized lipodystrophy

MONDO:0027766

Almost complete absence of subcutaneous and/or visceral adipose tissue.

Also known as: complete generalised lipodystrophy, complete generalized lipodystrophy

11 clinical trials for this condition and its sub-types.

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Sub-types

Congenital generalized lipodystrophy (1) Congenital generalized lipodystrophy type 3 (1) Acquired generalized lipodystrophy (0) Congenital generalized lipodystrophy type 1 (0) Congenital generalized lipodystrophy type 2 (0) Congenital generalized lipodystrophy type 4 (0) Lipodystrophy, congenital generalized, type 5 (0)

Broader categories

Disease (680) Metabolic disease (233) Skin disorder (132) Lipodystrophy (27) Human disease (14) Disease by body system or component (0) Disease by developmental or physiological process (0) Integumentary system disorder (0)

Trials to join now! 4 Not yet finished but already full! 1 Completed 5 Terminated 1

New hope for youngest kids with rare fat disorder

Disease control Terminated

This study tests a drug called metreleptin in 15 children under 6 years old who have a rare disease called generalized lipodystrophy, which prevents the body from storing fat properly and often leads to diabetes and high triglycerides. The goal is to see if the drug can lower blo…

Phase: PHASE3 • Sponsor: Amryt Pharma • Aim: Disease control

Last updated Jul 24, 2026 00:00 UTC