Esophageal atresia
MONDO:0001044A congenital abnormality of the esophagus in which the upper esophagus ends as a blind pouch and does not connect with the lower esophagus; it is often accompanied by a tracheoesophageal fistula. Signs and symptoms in a newborn with this abnormality include excessive salivation, choking, coughing, and the development of cyanosis and respiratory distress when fed.
Also known as: congenital atresia of esophagus, congenital atresia of oesophagus, congenital esophageal atresia, congenital imperforate oesophagus, esophageal atresia, esophageal atresia (disease), imperforate oesophagus
22 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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New hope for preventing Post-Surgery confusion in seniors
Symptom relief CompletedThis study tested whether giving a small amount of s-ketamine during chest surgery could reduce the risk of postoperative delirium (sudden confusion) in patients aged 60 and older. Over 500 participants were randomly assigned to receive either s-ketamine or another drug (dexmedet…
Phase: EARLY_PHASE1 • Sponsor: Affiliated Cancer Hospital & Institute of Guangzhou Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Study reveals dumping syndrome risk in babies after esophageal repair
Knowledge-focused CompletedThis study looked at 42 infants who had surgery for a rare birth defect called esophageal atresia type III. Researchers gave the babies a sugary drink to see how often they developed dumping syndrome, a condition causing rapid blood sugar changes. The goal was to find out how com…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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French registry sheds light on rare birth defect
Knowledge-focused CompletedThis study set up a national registry in France to track babies born with esophageal atresia, a birth defect where the esophagus is not fully formed. Researchers collected data on about 1,460 newborns to understand how common the condition is, what other health issues may occur, …
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Tiny biopsies may hold key to esophageal birth defect
Knowledge-focused CompletedThis study looked at tissue samples from 6 children born with esophageal atresia, a condition where the esophagus doesn't form properly. Researchers compared biopsies taken during surgery with those stored for up to a year to see if storage time changes the molecular information.…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Could a simple questionnaire unlock the secrets of Kids' eating disorders?
Knowledge-focused CompletedThis study tested a new parent questionnaire called ORALQUEST to assess feeding and eating disorders in children aged 9 months to 6 years. Researchers included 338 children with chronic conditions like heart defects or autism, as well as those with picky eating. The goal was to s…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC