Dumping syndrome
MONDO:0001979A disorder of the gastrointestinal tract. It is typically caused by the rapid emptying of undigested food from the stomach to the small intestine following gastroesophageal surgery but may be seen secondary to diabetes or the use of certain medications. Clinical signs may be seen 30-60 minutes after eating (early dumping): cramping, nausea, vomiting and diarrhea or they may be seen 1-3 hours later as a result of hyperinsulinemic hypoglycemia (late dumping): sweating, dizziness, confusion and heart palpitations. Untreated, the clinical course progresses to malnutrition and weight loss.
Also known as: jejunal syndrome
22 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New shot aims to stop dangerous sugar crashes after gastric bypass
Disease control CompletedThis study tests a new drug called MBX 1416 in 10 people who have low blood sugar episodes after weight loss surgery. Participants receive two injections of the drug, a low dose and a high dose, about two weeks apart. The goal is to see if the drug can raise the lowest blood suga…
Phase: PHASE2 • Sponsor: MBX Biosciences • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New drug shows promise for Post-Surgery sugar crashes
Disease control CompletedThis study tested a drug called mizagliflozin in 15 people who had gastric bypass surgery and suffer from dangerously low blood sugar after eating. The goal was to see if the drug could reduce these episodes and improve safety. The trial is now complete, and results will help det…
Phase: PHASE2 • Sponsor: Vogenx, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Study reveals dumping syndrome risk in babies after esophageal repair
Knowledge-focused CompletedThis study looked at 42 infants who had surgery for a rare birth defect called esophageal atresia type III. Researchers gave the babies a sugary drink to see how often they developed dumping syndrome, a condition causing rapid blood sugar changes. The goal was to find out how com…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC