New shot aims to stop dangerous sugar crashes after gastric bypass
NCT ID NCT07029412
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new drug called MBX 1416 in 10 people who have low blood sugar episodes after weight loss surgery. Participants receive two injections of the drug, a low dose and a high dose, about two weeks apart. The goal is to see if the drug can raise the lowest blood sugar level during a standard meal test, which could help control this condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MBX 1416 (imapextide)
What this could lead to
If this works, it could point toward a new treatment to prevent dangerous blood sugar drops after weight loss surgery, improving daily life and safety.
What could go wrong
This is a very small, early-phase study with only 10 participants, so results may not apply to everyone. The drug is given only twice, and its long-term safety and effectiveness are unknown.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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MBX Biosciences Investigational Site
RECRUITINGAurora, Colorado, 80045, United States
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MBX Biosciences Investigational Site
RECRUITINGMorehead City, North Carolina, 28557, United States
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MBX Biosciences Investigational Site
RECRUITINGKnoxville, Tennessee, 37920, United States
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MBX Biosciences Investigational Site
RECRUITINGSan Antonio, Texas, 78229, United States