Can a daily pill stop dangerous sugar drops after Weight-Loss surgery?

NCT ID NCT07760961

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial is testing an investigational drug called mizagliflozin to see if it can prevent low blood sugar (hypoglycemia) in people who experience this condition after bariatric surgery. The study will include adults who had Roux-en-Y bariatric surgery more than a year ago and have a history of reactive hypoglycemia. Participants will take either a low dose, a higher dose, or a placebo capsule three times a day for 28 days, and researchers will track how many low blood sugar episodes occur.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Mizagliflozin (an investigational drug taken as a capsule)
What this could lead to
If successful, this could lead to a new treatment option to prevent dangerous low blood sugar episodes in people who have had bariatric surgery.
What could go wrong
This is an early-stage trial with a small number of participants, so results may not be conclusive. The drug may not work as hoped or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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