Dental enamel hypoplasia
MONDO:0004038Deficiency in the enamel tissue that results in the formation of grooves, pits, or dents on the surface of the affected teeth.
Also known as: enamel hypoplasia
12 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
3D-Printed teeth: a better fit for kids?
Disease control CompletedThis trial tests whether 3D-printed crowns work better than standard stainless-steel crowns for restoring damaged first permanent molars in children. The study will compare how well each crown holds up, its effect on gum health, and how satisfied children and parents are with the…
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
-
Vitamin d mouthwash shows promise for Kids' chalky teeth
Disease control CompletedThis study tested whether a vitamin D mouthwash can help repair weak spots on children's permanent teeth (a condition called molar incisor hypomineralization) and improve gum health. Thirty-two children over age 6 used either a vitamin D or placebo mouthwash. Researchers measured…
Phase: PHASE1 • Sponsor: Cairo University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
-
New injection technique could fix Kids' tooth enamel without drilling
Disease control CompletedThis study tested a minimally invasive injection molding technique to restore front teeth affected by enamel hypoplasia in 14 children. The method uses a special resin injected into a clear stent to rebuild the tooth surface. The goal was to see how well the restoration holds up …
Phase: PHASE4 • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
-
New study tests better fillings for kids with sensitive teeth
Disease control CompletedThis study tested two types of dental overlays in 20 children aged 8-13 with Molar-Incisor Hypomineralisation (MIH), a condition that weakens enamel and causes tooth sensitivity. Each child received one overlay made from a hybrid composite and another from a hybrid ceramic, place…
Phase: NA • Sponsor: Alp Akça • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
-
Tooth resin treatment soothes sensitive teeth in children
Symptom relief CompletedThis study tested a resin coating on the front teeth of 40 children aged 7-14 who had weak enamel (hypomineralization or hypoplasia) and tooth sensitivity. The treatment aimed to reduce pain from cold air and improve how kids and parents felt about the look and function of their …
Phase: NA • Sponsor: Gizem Tıraşçı • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
-
Hunting for hidden genes behind tooth defects
Knowledge-focused CompletedThis study aims to discover new genes and mutations that cause isolated forms of amelogenesis imperfecta and dentinogenesis imperfecta—inherited conditions that affect tooth enamel and dentin. Researchers are using whole exome sequencing on participants who have these tooth disor…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
-
Quick lesson boosts Dentists-in-Training on tricky tooth condition
Knowledge-focused CompletedThis study tested whether a 30-minute interactive lesson could improve dental interns' understanding of Molar-Incisor Hypomineralization (MIH), a condition that causes weak spots on teeth. Two hundred dental interns from Future University in Egypt took a quiz before and after the…
Phase: NA • Sponsor: Future University in Egypt • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC