Corneal endothelial dystrophy
MONDO:0000766A corneal dystrophy (disease) that involves the corneal epithelium.
Also known as: corneal dystrophy (disease) of corneal epithelium, endothelial dystrophy
44 clinical trials for this condition and its sub-types.
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Broader categories
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Eye transplant showdown: which surgery saves sight best?
Disease control OngoingThis study compares two types of corneal transplant surgery (UT-DSAEK and DMEK) in 160 people with Fuchs dystrophy, a condition that clouds the cornea. It also tests whether a drug called rho-kinase inhibitor can reduce loss of important eye cells after surgery. The goal is to fi…
Phase: PHASE3 • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Lab-Grown eye cells injected to reverse corneal blindness
Disease control OngoingThis early-stage trial tests whether injecting cultured corneal endothelial cells into the eye can repair damaged corneas and improve vision. Twelve adults with corneal swelling and poor eyesight received a single injection of donor cells grown in a lab. The goal is to see if the…
Phase: PHASE1 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Contact lens stress test for fuchs dystrophy eyes
Knowledge-focused TerminatedThis study aimed to compare how corneas with Fuchs endothelial corneal dystrophy (FECD) and healthy corneas swell and recover after wearing a contact lens for three hours. Researchers planned to measure corneal thickness before and after the lens was removed, tracking swelling an…
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Does donor diabetes impact corneal transplant outcomes?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether corneas from donors with diabetes work as well as those from donors without diabetes after a specific type of corneal transplant called DMEK. Researchers will track 570 participants for 5 years to measure cell loss and overall transplant success. The g…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Free eye tests aim to catch vision loss early in harlem and washington heights
Knowledge-focused OngoingThis study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC